Trial reportAnnals of family medicine
Effects of enhanced depression treatment on diabetes self-care.
Trial report in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 10 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Pooled it
- Interventions to improve adherence to lipid-lowering medication.The Cochrane database of systematic reviews · 2016Pooled it
- Personalised care planning for adults with chronic or long-term health conditions.The Cochrane database of systematic reviews · 2015Pooled it
- Collaborative care for patients with depression and diabetes mellitus: a systematic review and meta-analysis.BMC psychiatry · 2013Pooled it
- Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression.The Cochrane database of systematic reviews · 2012Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Identifying psychosocial interventions that improve both physical and mental health in patients with diabetes: a systematic review and meta-analysis.Diabetes care · 2010Pooled it
- Depression and diabetes treatment nonadherence: a meta-analysis.Diabetes care · 2008Pooled it
- Pooled it
- Patient-Centered Outcomes of Medication Adherence Interventions: Systematic Review and Meta-Analysis.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes ResearchPooled it
- A randomized trial of comparing video telecare education vs. in-person education on dietary regimen compliance in patients with type 2 diabetes mellitus: a support for clinical telehealth Providers.BMC endocrine disorders · 2022Trial
- Distress and Type 2 Diabetes Self-Care: Putting the Pieces Together.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Trial
- A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in patients with uncontrolled type 2 diabetes.Diabetes care · 2014Trial
- The effect of enhanced depression care on adherence to risk-reducing behaviors after acute coronary syndromes: findings from the COPES trial.American heart journal · 2012Trial
- Behavioral health coaching for rural-living older adults with diabetes and depression: an open pilot of the HOPE Study.BMC geriatrics · 2012Trial
- Clinical complexity and the effectiveness of an intervention for depressed diabetes patients.Chronic illness · 2011Trial
- Trial
- Depression remission, receipt of problem-solving therapy, and self-care behavior frequency among low-income, predominantly Hispanic diabetes patients.General hospital psychiatryTrial
- Psychosocial interventions for diabetes distress in culturally diverse populations: a systematic scoping review.BMJ open · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
purposeAmong patients with diabetes, major depression is associated with more diabetic complications, lower medication adherence, and poorer self-care of diabetes. We reported earlier that enhanced depression care reduces depression symptoms but not hemoglobin A1c level. This study examined effects of depression interventions on self-management among depressed diabetic patients.
methodsA total of 329 patients in 9 primary care clinics were randomized to an evidence-based collaborative depression treatment (pharmacotherapy, problem-solving treatment, or both in combination) or usual primary care (routine medical services). Outcome measures included the Summary of Diabetes Self-Care Activities (SDSCA), reported at baseline and 3, 6, and 12 months, and medication non-adherence as assessed by automated pharmacy refill data of oral hypoglycemic agents, lipid-lowering agents, and angiotensin-converting enzyme inhibitors. We used mixed regression models adjusted for baseline differences to compare the intervention with usual care groups at follow-up assessments.
resultsDuring the 12-month intervention period, enhanced depression care and outcomes were not associated with improved diabetes self-care behaviors (healthy nutrition, physical activity, or smoking cessation). Relative to the usual care group, the intervention group reported a small decrease in body mass index (mean difference = 0.70 kg/m2, 95% CI, 0.17 to 1.24 kg/m2) and a higher rate of nonadherence to oral hypoglycemic agents (mean difference = -6.3%, 95% CI, -11.91% to -0.71%). Adherence to lipid-lowering agents and to antihypertensive medicines was similar for the 2 groups.
conclusionsIn general, diabetes self-management did not improve among the enhanced depression treatment group during a 12-month period, except for small between-group differences of limited clinical importance. Research needs to assess whether self-care interventions tailored for specific conditions, in addition to enhanced depression care, can achieve better diabetes and depression outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.