ArticleJournal of bacteriology1992
Identification of a putative eukaryotic-like protein kinase family in the developmental bacterium Myxococcus xanthus.
Article in Journal of bacteriology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- An atlas of bacterial serine-threonine kinases reveals functional diversity and key distinctions from eukaryotic kinases.Science signaling · 2025Article
- Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation.Microbiology (Reading, England) · 2010Article
- Article
- PhoR1-PhoP1, a third two-component system of the family PhoRP from Myxococcus xanthus: role in development.Journal of bacteriology · 2005Article
- Role of two novel two-component regulatory systems in development and phosphatase expression in Myxococcus xanthus.Journal of bacteriology · 2003Article
- Glycerol 3-phosphate inhibits swarming and aggregation of Myxococcus xanthus.Journal of bacteriology · 2001Article
- Myxococcus xanthus mokA encodes a histidine kinase-response regulator hybrid sensor required for development and osmotic tolerance.Journal of bacteriology · 2001Article
- Inhibition of development of Myxococcus xanthus by eukaryotic protein kinase inhibitors.Journal of bacteriology · 1998Article
- A chaperone in the HSP70 family controls production of extracellular fibrils in Myxococcus xanthus.Journal of bacteriology · 1998Article
- Diversity and specificity of protein-phosphorylating systems in bacteria.Folia microbiologica · 1997Review
- Effects of overexpression of Pkn2, a transmembrane protein serine/threonine kinase, on development of Myxococcus xanthus.Journal of bacteriology · 1996Article
- High mobility group I(Y)-like DNA-binding domains on a bacterial transcription factor.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Tyrosine phosphorylation in Myxococcus xanthus, a multicellular prokaryote.Journal of bacteriology · 1996Article
- Recent advances in the social and developmental biology of the myxobacteria.Microbiological reviews · 1996Review
- MlpA, a lipoprotein required for normal development of Myxococcus xanthus.Journal of bacteriology · 1995Article
- Genetics of gliding motility and development in Myxococcus xanthus.Archives of microbiology · 1995Review
- Germination of myxospores from the fruiting bodies of Myxococcus xanthus.Journal of bacteriology · 1995Article
- A mutant cysteinyl-tRNA synthetase affecting timing of chromosomal replication initiation in B. subtilis and conferring resistance to a protein kinase C inhibitor.The EMBO journal · 1994Article
- Evidence that asgB encodes a DNA-binding protein essential for growth and development of Myxococcus xanthus.Journal of bacteriology · 1994Article
- The PII protein in the cyanobacterium Synechococcus sp. strain PCC 7942 is modified by serine phosphorylation and signals the cellular N-status.Journal of bacteriology · 1994Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Myxococcus xanthus is a gram-negative bacterium which, upon starvation, undergoes a spectacular developmental cycle culminating in the formation of spore-filled fruiting bodies. We recently characterized a protein serine-threonine kinase (Pkn1) that is required for normal development (J. Munoz-Dorado, S. Inouye, and M. Inouye, Cell 67:995-1006, 1991). pkn1 was cloned by polymerase chain reaction amplification with primers designed from conserved sequences in eukaryotic protein kinases. In this study, a fragment of the pkn1 gene and an oligonucleotide corresponding to another highly conserved region were employed as probes for Southern blot analyses, which indicated that there are at least 26 putative kinase genes in M. xanthus. Most of the putative kinase genes were cloned, and complete or partial sequencing of eight clones revealed that they indeed contained highly conserved sequences present in eukaryotic kinases. These results suggest that complex kinase cascades similar to those described for eukaryotes might be involved in regulation of the M. xanthus life cycle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.