ArticleJournal of the American Society for Mass Spectrometry2006
Influence of crosslinker identity and position on gas-phase dissociation of Lys-Lys crosslinked peptides.
Article in Journal of the American Society for Mass Spectrometry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Cross-Linked α-Synuclein as Inhibitor of Amyloid Formation.International journal of molecular sciences · 2023Article
- Development of Large-scale Cross-linking Mass Spectrometry.Molecular & cellular proteomics : MCP · 2018Article
- Chemical cross-linking and mass spectrometry to determine the subunit interaction network in a recombinant human SAGA HAT subcomplex.Protein science : a publication of the Protein Society · 2015Article
- Imidate-based cross-linkers for structural proteomics: increased charge of protein and peptide ions and CID and ECD fragmentation studies.Journal of the American Society for Mass Spectrometry · 2014Article
- A negative ion mass spectrometry approach to identify cross-linked peptides utilizing characteristic disulfide fragmentations.Journal of the American Society for Mass Spectrometry · 2012Article
- The beginning of a beautiful friendship: cross-linking/mass spectrometry and modelling of proteins and multi-protein complexes.Journal of structural biology · 2011Article
- Elucidating the higher-order structure of biopolymers by structural probing and mass spectrometry: MS3D.Journal of mass spectrometry : JMS · 2010Article
- Collision-induced dissociation of Lys-Lys intramolecular crosslinked peptides.Journal of the American Society for Mass Spectrometry · 2009Article
- Impact of proline and aspartic acid residues on the dissociation of intermolecularly crosslinked peptides.Journal of the American Society for Mass Spectrometry · 2008Article
- Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides.Journal of molecular biology · 2007Article
- Current literature in mass spectrometry.Journal of mass spectrometry : JMS · 2007Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A systematic study of the dissociation patterns of crosslinked peptides analyzed by tandem mass spectrometry is reported. A series of 11-mer peptides was designed around either a polyalanine or polyglycine scaffold with arginine at the C terminus. One or two lysine residues were included at various locations within the peptides to effect inter- or intra-molecular crosslinking, respectively. Crosslinked species were generated with four commonly used amine-specific chemical crosslinking reagents: disuccinimidyl suberate (DSS), disuccinimidyl tartarate (DST), dithiobis(succinimidylpropionate) (DSP), and disuccinimidyl glutarate (DSG). The influence of precursor charge state, location of crosslink, and specific crosslinking reagent on the MS/MS dissociation pattern was examined. Observed trends in the dissociation patterns obtained for these species will allow for improvements to software used in the automated interpretation of crosslinked peptide MS/MS data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.