ReviewJournal of physiology and biochemistry2005
Inflammation and conjugated linoleic acid: mechanisms of action and implications for human health.
Review in Journal of physiology and biochemistry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Effect of conjugated linoleic acid on blood inflammatory markers: a systematic review and meta-analysis on randomized controlled trials.European journal of clinical nutrition · 2018Pooled it
- Pooled it
- Metabolically healthy obesity and metabolically obese normal weight: a review.Journal of physiology and biochemistry · 2021Review
- An integrated metabolomics and 16S rRNA gene sequencing approach exploring the molecular pathways and potential targets behind the effects of Radix Scrophulariae.RSC advances · 2019Article
- Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism.Metabolomics : Official journal of the Metabolomic Society · 2016Article
- Effects of pterostilbene in brown adipose tissue from obese rats.Journal of physiology and biochemistry · 2016Article
- Nutrigenomic Functions of PPARs in Obesogenic Environments.PPAR research · 2016Review
- Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes.Free radical biology & medicine · 2015Article
- Fecal metabolomics: assay performance and association with colorectal cancer.Carcinogenesis · 2014Article
- Fatty acids, inflammation, and asthma.The Journal of allergy and clinical immunology · 2014Review
- Article
- Conjugated linoleic acid is a preferential substrate for fatty acid nitration.The Journal of biological chemistry · 2012Article
- Precision genetics for complex objectives in animal agriculture.Journal of animal science · 2010Article
- Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus.BMC complementary and alternative medicine · 2009Article
- Isomer specificity of conjugated linoleic acid (CLA): 9E,11E-CLA.Nutrition research and practice · 2008Article
- Article
- Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression.Lipids · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data from a number of studies and trials have shown that different conjugated linoleic acids (CLA's) may produce beneficial effects on cancer, atherosclerosis, hypertension, diabetes and changes in body composition. Despite the increasing knowledge about CLA's implications on health, the mechanism of action of these fatty acids is not completely understood. Moreover, human studies indicate that some of these beneficial effects are considerably less evident than anticipated from mice studies, while the efficacy and safety of dietary supplements containing CLA have been questioned in some intervention trials. Recently, it has been suggested that the anti-carcinogenic and anti-atherosclerosis effects of CLA's stem from its anti-inflammatory properties. Because inflammatory responses are associated with the pathophysiology of many diseases, including obesity and the metabolic syndrome, the investigation in this area is of growing interest in recent years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.