Evidence map›Paper›PMID 16437674›Full record

Trial reportWorld journal of gastroenterology2005

Effect of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.

Ke-Xia Wang, Li-Hua Zhang, Jiang-Long Peng, Yong Liang, Xue-Feng Wang, Hui Zhi, Xiang-Xia Wang, Huan-Xiong Geng

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ke-Xia WangDepartment of Pathogenic Biology, School of Medicine, Anhui University of Science and Technology, Huainan 232001, Anhui Province, China. cpli@aust.edu.cn
Li-Hua Zhang
Jiang-Long Peng
Yong Liang
Xue-Feng Wang
Hui Zhi
Xiang-Xia Wang
Huan-Xiong Geng
Anhui University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.

methodsThe levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole.

resultsAfter one course of treatment with liniment levamisole, the levels of CD3(+), CD4(+), and the ratio of CD4(+)/CD8(+) increased as compared to those before the treatment but the level of CD8(+) decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole.

conclusionLiniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.

Indexed as

Adjuvants, ImmunologicAdultFemaleHepatitis B, ChronicHumansImmunity, CellularLevamisoleLinimentsMaleMiddle AgedT-Lymphocyte SubsetsAdjuvants, ImmunologicLevamisoleLiniments

Identifiers

PMID16437674
PMCPMC4725075
OpenAlexW1019994822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.