ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2006
Biocompatibility testing of novel multifunctional polymeric biomaterials for tissue engineering applications in head and neck surgery: an overview.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- 3D Printing for Tissue Engineering: Printing Techniques, Biomaterials, Challenges, and the Emerging Role of 4D Bioprinting.Bioengineering (Basel, Switzerland) · 2025Review
- In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs.Current issues in molecular biology · 2024Article
- Current Trends in Biomedical Hydrogels: From Traditional Crosslinking to Plasma-Assisted Synthesis.Polymers · 2022Review
- Poly-ε-Caprolactone-Hydroxyapatite-Alumina (PCL-HA-α-AlPolymers · 2022Article
- Innovative Design Methodology for Patient-Specific Short Femoral Stems.Materials (Basel, Switzerland) · 2022Article
- On the Biocompatibility and Teat Retention of In Situ Gelling Intramammary Formulations: Cattle Mastitis Prevention and Treatment.Pharmaceutics · 2021Article
- The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents.Micromachines · 2021Review
- On-command on/off switching of progenitor cell and cancer cell polarized motility and aligned morphology via a cytocompatible shape memory polymer scaffold.Biomaterials · 2017Article
- Cytotoxicity Evaluation of Anatase and Rutile TiO₂ Thin Films on CHO-K1 Cells in Vitro.Materials (Basel, Switzerland) · 2016Article
- Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites.Journal of visualized experiments : JoVE · 2016Article
- Shape-memory surfaces for cell mechanobiology.Science and technology of advanced materials · 2015Review
- Biocompatibility and Surface Properties of TiO₂ Thin Films Deposited by DC Magnetron Sputtering.Materials (Basel, Switzerland) · 2014Article
- Application of the chick embryo chorioallantoic membrane in neurosurgery disease.International journal of medical sciences · 2014Review
- Biomedical applications of thermally activated shape memory polymers.Journal of materials chemistry · 2010Article
- Cartilage replacement by use of hybrid systems of autologous cells and polyethylene: an experimental study.Journal of materials science. Materials in medicine · 2009Article
- Polymeric implant materials for the reconstruction of tracheal and pharyngeal mucosal defects in head and neck surgery.GMS current topics in otorhinolaryngology, head and neck surgery · 2009Article
- A review of the biocompatibility of implantable devices: current challenges to overcome foreign body response.Journal of diabetes science and technology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomaterial research and tissue engineering are rapidly growing scientific fields that need an interdisciplinary approach where clinicians should be included from the onset. Biocompatibility testing in vitro and in vivo comprise the agarose-overlay test, the MTT test, direct cell seeding tests and the chorioallantoic membrane test for angiogenic effects, among others. Molecular biology techniques such as real-time polymerase chain reaction and microarray technology facilitate the investigation of tissue integration into biomaterials on a cellular and molecular level. The physicochemical characterization of biomaterials is conducted using such methods as X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). Excellent biocompatibility and biofunctionality were demonstrated for a series of recently developed multifunctional biodegradable, polymeric biomaterials both in vitro and in vivo. Novel, multifunctional polymeric biomaterials offer a highly specific adjustment to the physiological, anatomical and surgical requirements and can thereby facilitate new therapeutic options in head and neck surgery.
Indexed as
Identifiers
16437250What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.