Evidence map›Paper›PMID 16435128›Full record

ReviewCancer immunology, immunotherapy : CII2006

Tumor immune escape mechanisms: impact of the neuroendocrine system.

Kerstin Lang, Frank Entschladen, Corinna Weidt, Kurt S Zaenker

Abstract readReview
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Depression, mood, stress, and Th1/Th2 immune balance in primary breast cancer patients undergoing classical massage therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011
    Trial
  2. Article
  3. Role of the brain-gut axis in gastrointestinal cancer.World journal of clinical cases · 2019
    Review
  4. Role of Endogenous Glucocorticoids in Cancer in the Elderly.International journal of molecular sciences · 2018
    Review
  5. Article
  6. Review
  7. Article
  8. Neuroendocrine influences on cancer biology.Seminars in cancer biology · 2008
    Review
  9. Review
  10. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kerstin LangInstitute of Immunology, Witten/Herdecke University, Stockumer Str. 10, 58448 Witten, Germany. lang@uni-wh.de
Frank Entschladen
Corinna Weidt
Kurt S Zaenker

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor cells act upon, and react to both their proximate and more distant environment, the mechanisms by which this is achieved being both autocrine and paracrine in nature. This interaction, however, takes place not only between adjacent malignant cells, but also non-malignant cells such as those of the immune system, the latter also partaking in the modeling of the tumor environment. Although tumor cells descend from normal tissue cells and thus bear in classical immunological terms 'self signals', it is evident that the immune system is able to recognize tumor cells as a harassment for the body and in consequence tries to eliminate these cells. On the counterpart, tumor cells acquire various characteristics which allow them to evade this immunological surveillance, and have been collectively coined with the term "tumor escape mechanisms". This review will describe and summarize current understanding of tumor escape strategies, and also more closely elaborate on the modulatory role of the neuroendocrine system in the immune system-tumor cell interaction.

Indexed as

AnimalsAntigen PresentationAntigens, NeoplasmCell FusionDepressionFas Ligand ProteinHumansInflammationKiller Cells, NaturalMembrane GlycoproteinsMiceModels, BiologicalNeoplasm MetastasisNeoplasm ProteinsNeoplasms, ExperimentalNerve Growth FactorsAntigens, NeoplasmFASLG protein, humanFas Ligand ProteinFasl protein, mouseMembrane GlycoproteinsNeoplasm ProteinsNerve Growth FactorsNeurotransmitter AgentsTumor Necrosis Factors

Identifiers

PMID16435128
PMCPMC11030197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.