ArticleBMC bioinformatics2006
MitoRes: a resource of nuclear-encoded mitochondrial genes and their products in Metazoa.
Article in BMC bioinformatics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures.PloS one · 2023Article
- mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations.Nucleic acids research · 2020Article
- MitProNet: A knowledgebase and analysis platform of proteome, interactome and diseases for mammalian mitochondria.PloS one · 2014Article
- Spatial and functional organization of mitochondrial protein network.Scientific reports · 2013Article
- MitoMiner: a data warehouse for mitochondrial proteomics data.Nucleic acids research · 2012Article
- Network clustering revealed the systemic alterations of mitochondrial protein expression.PLoS computational biology · 2011Article
- MitoGenesisDB: an expression data mining tool to explore spatio-temporal dynamics of mitochondrial biogenesis.Nucleic acids research · 2011Article
- DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.Circulation research · 2010Article
- Neurodevelopmental manifestations of mitochondrial disease.Journal of developmental and behavioral pediatrics : JDBP · 2010Review
- Computational annotation of UTR cis-regulatory modules through Frequent Pattern Mining.BMC bioinformatics · 2009Article
- MitoMiner, an integrated database for the storage and analysis of mitochondrial proteomics data.Molecular & cellular proteomics : MCP · 2009Article
- Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster.Genome research · 2008Article
- Comprehensive DNA barcode coverage of North American birds.Molecular ecology notes · 2007Article
- Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions.Journal of proteome research · 2007Article
- V-MitoSNP: visualization of human mitochondrial SNPs.BMC bioinformatics · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMitochondria are sub-cellular organelles that have a central role in energy production and in other metabolic pathways of all eukaryotic respiring cells. In the last few years, with more and more genomes being sequenced, a huge amount of data has been generated providing an unprecedented opportunity to use the comparative analysis approach in studies of evolution and functional genomics with the aim of shedding light on molecular mechanisms regulating mitochondrial biogenesis and metabolism. In this context, the problem of the optimal extraction of representative datasets of genomic and proteomic data assumes a crucial importance. Specialised resources for nuclear-encoded mitochondria-related proteins already exist; however, no mitochondrial database is currently available with the same features of MitoRes, which is an update of the MitoNuc database extensively modified in its structure, data sources and graphical interface. It contains data on nuclear-encoded mitochondria-related products for any metazoan species for which this type of data is available and also provides comprehensive sequence datasets (gene, transcript and protein) as well as useful tools for their extraction and export. DESCRIPTION: MitoRes http://www2.ba.itb.cnr.it/MitoRes/ consolidates information from publicly external sources and automatically annotates them into a relational database. Additionally, it also clusters proteins on the basis of their sequence similarity and interconnects them with genomic data. The search engine and sequence management tools allow the query/retrieval of the database content and the extraction and export of sequences (gene, transcript, protein) and related sub-sequences (intron, exon, UTR, CDS, signal peptide and gene flanking regions) ready to be used for in silico analysis.
conclusionThe tool we describe here has been developed to support lab scientists and bioinformaticians alike in the characterization of molecular features and evolution of mitochondrial targeting sequences. The way it provides for the retrieval and extraction of sequences allows the user to overcome the obstacles encountered in the integrative use of different bioinformatic resources and the completeness of the sequence collection allows intra- and interspecies comparison at different biological levels (gene, transcript and protein).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.