ArticleSurgical endoscopy2006
Laparoscopic surgery in children is associated with an intraoperative hypermetabolic response.
Article in Surgical endoscopy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 32 citations in OpenAlex.
- Inflammatory response after open and laparoscopic Nissen fundoplication in children: a randomized study.Pediatric surgery international · 2014Trial
- Comparing Surgical Stress in Children Undergoing Open and Laparoscopic Inguinal Hernioplasty-A Single Center's Prospective Study Results.Children (Basel, Switzerland) · 2025Article
- Predictive value of the respiratory exchange ratio for the occurrence of postoperative complications in laparoscopic surgery: a prospective and observational study.Journal of clinical monitoring and computing · 2021Observational
- Nephrectomy in children: Comparison of stress response to laparoscopic and open methods.Journal of Indian Association of Pediatric Surgeons · 2013Article
- [Minimally invasive pediatric surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2010Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic surgery is thought to be associated with a reduced metabolic response compared to open surgery. Oxygen consumption (VO2) and energy metabolism during laparoscopic surgery have not been characterized in children.
methodsWe measured respiratory gas exchange intraoperatively in children undergoing 19 open and 20 laparoscopic procedures. Premature infants and patients with metabolic, renal, and cardiac abnormalities were excluded. Anesthesia was standardized. Unheated carbon dioxide was used for insufflation. VO2 was measured by indirect calorimetry. Core temperature was measured using an esophageal temperature probe.
resultsWe found a steady increase in VO2 during laparoscopy. The increase in VO2 was more marked in younger children and was associated with a significant rise in core temperature. Open surgery was not associated with significant changes in core temperature or VO2.
conclusionsLaparoscopy in children is associated with an intraoperative hypermetabolic response characterized by increased oxygen consumption and core temperature. These changes are more marked in younger children.
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Registered trials
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