ArticleProceedings of the National Academy of Sciences of the United States of America2006
Theory of the deuterium NMR of sterol-phospholipid membranes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Sterol and lipid metabolism in bees.Metabolomics : Official journal of the Metabolomic Society · 2023Review
- OxPAPC stabilizes liquid-ordered domains in biomimetic membranes.Biophysical journal · 2023Article
- Cholesterol access in cellular membranes controls Hedgehog signaling.Nature chemical biology · 2020Review
- Fluid Phase Coexistence in Biological Membrane: Insights from Local Nonaffine Deformation of Lipids.Biophysical journal · 2018Article
- The Phase Behavior and Organization of Sphingomyelin/Cholesterol Membranes: A Deuterium NMR Study.Biophysical journal · 2018Article
- Switch-like responses of two cholesterol sensors do not require protein oligomerization in membranes.Biophysical journal · 2015Article
- Comparative study of the interaction of fullerenol nanoparticles with eukaryotic and bacterial model membranes using solid-state NMR and FTIR spectroscopy.European biophysics journal : EBJ · 2012Article
- A simple thermodynamic model of the liquid-ordered state and the interactions between phospholipids and cholesterol.Biophysical journal · 2011Article
- Accessibility of cholesterol in endoplasmic reticulum membranes and activation of SREBP-2 switch abruptly at a common cholesterol threshold.The Journal of biological chemistry · 2010Article
- Phase separations in binary and ternary cholesterol-phospholipid mixtures.Biophysical journal · 2010Article
- Influence of cholesterol on the collective dynamics of the phospholipid acyl chains in model membranes.The European physical journal. E, Soft matter · 2010Article
- Effect of cholesterol on structural and mechanical properties of membranes depends on lipid chain saturation.Physical review. E, Statistical, nonlinear, and soft matter physics · 2009Article
- Effects of cholesterol and unsaturated DOPC lipid on chain packing of saturated gel-phase DPPC bilayers.General physiology and biophysics · 2009Article
- Article
- Multiscale simulations of heterogeneous model membranes.Biochimica et biophysica acta · 2009Review
- Molecular motion at the critical point in lipid membranes.Biophysical journal · 2008Article
- Order parameters and areas in fluid-phase oriented lipid membranes using wide angle X-ray scattering.Biophysical journal · 2008Article
- Use of fluorescence to determine the effects of cholesterol on lipid behavior in sphingomyelin liposomes and erythrocyte membranes.Journal of lipid research · 2008Article
- Cholesterol perturbs lipid bilayers nonuniversally.Physical review letters · 2008Article
- Cholesterol is a determinant of the structures of discoidal high density lipoproteins formed by the solubilization of phospholipid membranes by apolipoprotein A-I.Biochimica et biophysica acta · 2008Article
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2 authors.
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Abstract
A general theoretical model is described for the NMR spectra of mixtures of sterols and deuterium-labeled phospholipids. In the case of homogeneous membranes, the average quadrupole splittings are determined by equilibria between lipids in cholesterol-phospholipid complexes and lipids not in complexes. Chemical exchange of lipids between those in the free state and those in the complex state affects the deuterium resonance line shapes. The lifetime of a phospholipid molecule in an ergosterol-dipalmitoylphosphatidylcholine complex is estimated to be of the order of 10(-5) s on the basis of the observed line broadenings. In the vicinity of a critical point of a cholesterol-phospholipid mixture, fluctuations in the concentration of complexes also can contribute to the deuterium nuclear resonance line broadening. At the critical point, the temperature derivative of the concentration of complexes is discontinuous. There is a corresponding jump in the calculated heat capacity as well as in the temperature derivative of the deuterium NMR first moment.
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