ArticleInfection and immunity2006
Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Mycobacterium tuberculosis strain with deletions in menT3 and menT4 is attenuated and confers protection in mice and guinea pigs.Nature communications · 2024Article
- Review
- Animal Models of Tuberculosis Vaccine Research: An Important Component in the Fight against Tuberculosis.BioMed research international · 2020Review
- The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease.Pathogens and disease · 2019Review
- Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs.Frontiers in microbiology · 2019Article
- Development and utilization of a custom PCR array workflow: analysis of gene expression in mycoplasma genitalium and guinea pig (Cavia porcellus).Molecular biotechnology · 2015Article
- Animal models of tuberculosis: Guinea pigs.Cold Spring Harbor perspectives in medicine · 2014Review
- Whole genome response in guinea pigs infected with the high virulence strain Mycobacterium tuberculosis TT372.Tuberculosis (Edinburgh, Scotland) · 2014Article
- The impact of "omic" and imaging technologies on assessing the host immune response to biodefence agents.Journal of immunology research · 2014Review
- Article
- Article
- Development of the first oligonucleotide microarray for global gene expression profiling in guinea pigs: defining the transcription signature of infectious diseases.BMC genomics · 2012Article
- Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax.The American journal of pathology · 2011Article
- Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice.Investigative ophthalmology & visual science · 2009Article
- Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth.BMC medical genomics · 2009Article
- Using guinea pigs in studies relevant to asthma and COPD.Pulmonary pharmacology & therapeutics · 2008Review
- The guinea pig as a model of infectious diseases.Comparative medicine · 2008Review
- Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig.Tuberculosis (Edinburgh, Scotland) · 2008Article
- Immune gene networks of mycobacterial vaccine-elicited cellular responses and immunity.The Journal of infectious diseases · 2007Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune responses in the guinea pig model are understudied because of a lack of commercial reagents. We have developed a custom-made guinea pig oligonucleotide microarray (81 spots) and have examined the gene expression profile of splenocytes restimulated in vitro from Mycobacterium bovis BCG-vaccinated and naive animals. Eleven genes were significantly (P < 0.05) up-regulated following vaccination, indicating a Th1-type response. These results show that microarrays can be used to more fully define immune profiles of guinea pigs.
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