ArticleInfection and immunity2006
Killed Candida albicans yeasts and hyphae inhibit gamma interferon release by murine natural killer cells.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Human natural killer cells exhibit potent antifungal activity against azole-resistantMicrobiology spectrum · 2026Article
- In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes inCurrent issues in molecular biology · 2024Article
- Select Streptococci Can DegradeApplied and environmental microbiology · 2022Article
- Thrombin-Derived C-Terminal Peptide ReducesAntimicrobial agents and chemotherapy · 2021Article
- Renal CD169Life science alliance · 2021Article
- Microbiome in human cancers.Access microbiology · 2021Review
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).European journal of immunology · 2019Article
- Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.JCI insight · 2018Article
- Guidelines for the use of flow cytometry and cell sorting in immunological studies.European journal of immunology · 2017Article
- NK Cells and Their Role in Invasive Mold Infection.Journal of fungi (Basel, Switzerland) · 2017Review
- Innate immune cell response upon Candida albicans infection.Virulence · 2016Review
- Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis.PLoS pathogens · 2015Article
- Natural killer cells and antifungal host response.Clinical and vaccine immunology : CVI · 2013Review
- Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.British journal of pharmacology · 2012Review
- Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia.The Journal of infectious diseases · 2011Article
- Pattern recognition receptors in companion and farm animals - the key to unlocking the door to animal disease?Veterinary journal (London, England : 1997) · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Killed yeasts and hyphae of Candida albicans inhibit gamma interferon secretion by highly purified murine NK cells in response to the Toll-like receptor ligands lipopolysaccharide and zymosan. This effect, which is also observed in the presence of NK-activating cytokines (interleukin-2 [IL-2], IL-12, and IL-15), may represent a novel mechanism of immune evasion that contributes to the virulence of C. albicans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.