Evidence map›Paper›PMID 16428792›Full record

ArticleInfection and immunity2006

Salmonella enterica serovar Typhimurium ompS1 and ompS2 mutants are attenuated for virulence in mice.

Olivia Rodríguez-Morales, Marcos Fernández-Mora, Ismael Hernández-Lucas, Alejandra Vázquez, José Luis Puente, Edmundo Calva

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  7. Gene Expression Response ofFrontiers in microbiology · 2017
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Olivia Rodríguez-MoralesDepartamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Cuernavaca, Morelos 62210, México.
Marcos Fernández-Mora
Ismael Hernández-Lucas
Alejandra Vázquez
José Luis Puente
Edmundo Calva
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonella enterica serovar Typhimurium mutants with mutations in the ompS1 and ompS2 genes, which code for quiescent porins, were nevertheless highly attenuated for virulence in a mouse model, indicating a role in pathogenesis. Similarly, a strain with a mutation in the gene coding for LeuO, a positive regulator of ompS2, was also attenuated.

Indexed as

MutationAnimalsBacterial Outer Membrane ProteinsCell LineEscherichia coli ProteinsFemaleHeLa CellsHumansMacrophagesMiceMice, Inbred BALB CSalmonella Infections, AnimalSalmonella typhimuriumTranscription FactorsVirulenceBacterial Outer Membrane ProteinsEscherichia coli ProteinsLeuO protein, E coliTranscription Factors

Identifiers

PMID16428792
PMCPMC1360296
OpenAlexW2129662008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.