ArticlePlant physiology2006
The Arabidopsis zinc finger-homeodomain genes encode proteins with unique biochemical properties that are coordinately expressed during floral development.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.
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Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it, 177 citations in OpenAlex.
- Interplay among ZF-HD and GRF transcription factors during Arabidopsis leaf development.Plant physiology · 2023Pooled it
- Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Bi-functional transcription factor FnZHD9 regulates leaf curling and drought resistance in fragaria nilgerrensis.BMC plant biology · 2026Article
- Article
- Integrating 3D imaging, GWAS, and single-cell transcriptome approaches to elucidate root system architecture in Populus.Plant physiology · 2025Article
- A homeobox transcription factor HB34 suppresses jasmonic acid biosynthesis but promotes the expression of growth-related genes to balance plant immunity and growth in Arabidopsis.Plant communications · 2025Article
- The OsZHD1 and OsZHD2, Two Zinc Finger Homeobox Transcription Factor, Redundantly Control Grain Size by Influencing Cell Proliferation in Rice.Rice (New York, N.Y.) · 2025Article
- Genome-wide identification and expression analysis of ZF-HD family in sunflower (Helianthus annuus L.) under drought and salt stresses.BMC plant biology · 2025Article
- The members of zinc finger-homeodomain (ZF-HD) transcription factors are associated with abiotic stresses in soybean: insights from genomics and expression analysis.BMC plant biology · 2025Article
- Molecular Mechanisms Associated with Plant Tolerance upon Abiotic Stress.Plants (Basel, Switzerland) · 2024Article
- ZF-HD gene family in rapeseed (Brassica napus L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses.BMC genomics · 2024Article
- N6-methyladenosine RNA modification regulates photoperiod sensitivity in cotton.Plant physiology · 2024Article
- Modeling Chickpea Productivity with Artificial Image Objects and Convolutional Neural Network.Plants (Basel, Switzerland) · 2024Article
- Systematic Analysis of Zinc Finger-Homeodomain Transcription Factors (ZF-HDs) in Barley (Genes · 2024Article
- Zinc Finger-Homeodomain Transcriptional Factors (ZHDs) in Cucumber (International journal of molecular sciences · 2024Article
- An miR164-resistant mutation in the transcription factor gene CpCUC2B enhances carpel arrest and ectopic boundary specification in Cucurbita pepo flower development.Journal of experimental botany · 2024Article
- Genome-Wide Identification and Analysis ofPlants (Basel, Switzerland) · 2023Article
- In silico and computational analysis of zinc finger motif-associated homeodomain (ZF-HD) family genes in chilli (Capsicum annuum L).BMC genomics · 2023Article
- Genomic basis of multiphase evolution driving divergent selection of zinc-finger homeodomain genes.Nucleic acids research · 2023Article
- Endosperm Persistence inPlants (Basel, Switzerland) · 2023Article
28 more citing papers are in PubMed but not listed here.
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis (Arabidopsis thaliana) contains approximately 100 homeobox genes, many of which have been shown to play critical roles in various developmental processes. Here we characterize the zinc finger-homeodomain (ZF-HD) subfamily of homeobox genes, consisting of 14 members in Arabidopsis. We demonstrate that the HDs of the ZF-HD proteins share some similarities with other known HDs in Arabidopsis, but they contain distinct features that cluster them as a unique class of plant HD-containing proteins. We have carried out mutational analyses to show that the noncanonical residues present in the HDs of this family of proteins are important for function. Yeast (Saccharomyces cerevisiae) two-hybrid matrix analyses of the ZF-HD proteins reveal that these proteins both homo- and heterodimerize, which may contribute to greater selectivity in DNA binding. These assays also show that most of these proteins do not contain an intrinsic activation domain, suggesting that interactions with other factors are required for transcriptional activation. We also show that the family members are all expressed predominantly or exclusively in floral tissue, indicating a likely regulatory role during floral development. Furthermore, we have identified loss-of-function mutations for six of these genes that individually show no obvious phenotype, supporting the idea that the encoded proteins have common roles in floral development. Based on these results, we propose the ZF-HD gene family encodes a group of transcriptional regulators with unique biochemical activities that play overlapping regulatory roles in Arabidopsis floral development.
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