Evidence map›Paper›PMID 16426445›Full record

ArticleBMC infectious diseases2006

Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatella species.

Laurence Senn, José M Entenza, Gilbert Greub, Katia Jaton, Aline Wenger, Jacques Bille, Thierry Calandra, Guy Prod'hom

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 94 citations in OpenAlex.

  1. Granulicatella adiacens infections in children: a single-center retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Association of infective endocarditis caused byJournal of cardiology cases · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. International journal of molecular sciences · 2021
    Article
  12. Article
  13. Atypical presentation ofClinical case reports · 2021
    Article
  14. Case reports in infectious diseases · 2019
    Article
  15. Antimicrobial Susceptibilities of Oral Isolates ofMedicines (Basel, Switzerland) · 2018
    Article
  16. Aortitis caused byInfectious disease reports · 2018
    Article
  17. BMJ case reports · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Laurence SennInfectious Diseases Service, University Hospital, Lausanne, Switzerland. laurence.senn@chuv.ch
José M Entenza
Gilbert Greub
Katia Jaton
Aline Wenger
Jacques Bille
Thierry Calandra
Guy Prod'hom
University Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbiotrophia and Granulicatella species, previously referred to as nutritionally variant streptococci (NVS), are significant causative agents of endocarditis and bacteraemia. In this study, we reviewed the clinical manifestations of infections due to A. defectiva and Granulicatella species that occurred at our institution between 1998 and 2004.

methodsThe analysis included all strains of NVS that were isolated from blood cultures or vascular graft specimens. All strains were identified by 16S rRNA sequence analysis. Patients' medical charts were reviewed for each case of infection.

resultsEleven strains of NVS were isolated during the 6-year period. Identification of the strains by 16S rRNA showed 2 genogroups: Abiotrophia defectiva (3) and Granulicatella adiacens (6) or "para-adiacens" (2). The three A. defectiva strains were isolated from immunocompetent patients with endovascular infections, whereas 7 of 8 Granulicatella spp. strains were isolated from immunosuppressed patients, mainly febrile neutropenic patients. We report the first case of "G. para-adiacens" bacteraemia in the setting of febrile neutropenia.

conclusionWe propose that Granulicatella spp. be considered as a possible agent of bacteraemia in neutropenic patients.

Indexed as

AdultBacteremiaEndocarditis, BacterialFemaleHumansInfantMaleMicrobial Sensitivity TestsMiddle AgedNeutropeniaPhylogenyRNA, Ribosomal, 16SStreptococcaceaeRNA, Ribosomal, 16S

Identifiers

PMID16426445
PMCPMC1360077
OpenAlexW2120030207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.