Evidence map›Paper›PMID 16426014›Full record

ArticleClinical and vaccine immunology : CVI2006

Ultrasensitive human immunodeficiency virus type 1 p24 antigen assay modified for use on dried whole-blood spots as a reliable, affordable test for infant diagnosis.

Janet C Patton, Gayle G Sherman, Ashraf H Coovadia, Wendy S Stevens, Tammy M Meyers

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Comparison of the Gen-Probe Aptima HIV-1 and Abbott HIV-1 qualitative assays with the Roche Amplicor HIV-1 DNA assay for early infant diagnosis using dried blood spots.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014
    Article
  6. An overview of the clinical use of filter paper in the diagnosis of tropical diseases.The American journal of tropical medicine and hygiene · 2014
    Review
  7. Analysis of the optimal cut-point for HIV-p24 antigen testing to diagnose HIV infection in HIV-exposed children from resource-constrained settings.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2011
    Article
  8. Using a simplified human immunodeficiency virus type 1 p24 antigen assay to diagnose pediatric HIV-infection in Malawi.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2010
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Janet C PattonWits Paediatric HIV Unit, Wits Health Consortium, University of the Witwatersrand, 7 York Rd., Parktown 2193, Johannesburg, South Africa. janet.patton@nhls.ac.za
Gayle G Sherman
Ashraf H Coovadia
Wendy S Stevens
Tammy M Meyers
University of the Witwatersrand · ZANational Health Laboratory Service · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ultrasensitive human immunodeficiency virus (HIV) p24 antigen assay was modified for use on pediatric dried whole-blood spots on Whatman no. 1 filter paper. The modified assay was found to be reliable and accurate, making it an affordable tool for pediatric HIV diagnosis in developing countries.

Indexed as

Neonatal ScreeningBlood Chemical AnalysisDesiccationEnzyme-Linked Immunosorbent AssayHIV-1HIV Core Protein p24HIV InfectionsHumansInfant, NewbornSensitivity and SpecificityHIV Core Protein p24

Identifiers

PMID16426014
PMCPMC1356617
OpenAlexW2157866544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.