Evidence map›Paper›PMID 16425426›Full record

ArticleWorld journal of gastroenterology2005

Effects of Helicobacter pylori eradication on atrophic gastritis and intestinal metaplasia: a 3-year follow-up study.

Bin Lu, Ming-Tao Chen, Yi-Hong Fan, Yan Liu, Li-Na Meng

Abstract readControlled Clinical Trial
In one paragraph

Article in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. World journal of gastroenterology · 2021
    Review
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  8. Clinical background factors affecting outcomes ofJournal of general and family medicine · 2019
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  16. Rate and predictive factors ofSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bin LuDepartment of Gastroenterology, Affiliated Hospital of Zhejiang Traditional Chinese Medicine College, Hangzhou 310006, Zhejiang Province China. lvbin@medmail.com.cn
Ming-Tao Chen
Yi-Hong Fan
Yan Liu
Li-Na Meng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of H pylori eradication on atrophic gastritis and intestinal metaplasia (IM).

methodsTwo hundred and fifty-nine patients with atrophic gastritis in the antrum were included in the study, 154 patients were selected for H pylori eradication therapy and the remaining 105 patients served as untreated group. Gastroscopy and biopsies were performed both at the beginning and at the end of a 3-year follow-up study. Gastritis was graded according to the updated Sydney system.

resultsOne hundred and seventy-nine patients completed the follow-up, 92 of them received H pylori eradication therapy and the remaining 87 H pylori-infected patients were in the untreated group. Chronic gastritis, active gastritis and the grade of atrophy significantly decreased in H pylori eradication group (P<0.01). However, the grade of IM increased in H pylori -infected group (P<0.05).

conclusionH pylori eradication may improve gastric mucosal inflammation, atrophy and prevent the progression of IM.

Indexed as

Helicobacter pyloriAdultAgedAnti-Bacterial AgentsFemaleFollow-Up StudiesGastritis, AtrophicHelicobacter InfectionsHumansMaleMetaplasiaMiddle AgedPrecancerous ConditionsAnti-Bacterial Agents

Identifiers

PMID16425426
PMCPMC4355796

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.