Evidence map›Paper›PMID 16421722›Full record

ArticleCancer immunology, immunotherapy : CII2006

ESTDAB: a collection of immunologically characterised melanoma cell lines and searchable databank.

Graham Pawelec, Steven G Marsh

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
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  8. IPD--the Immuno Polymorphism Database.Nucleic acids research · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
  13. IPD--the Immuno Polymorphism Database.Nucleic acids research · 2010
    Article
  14. Article
  15. Article
  16. Review
  17. The European searchable tumour line database.Cancer immunology, immunotherapy : CII · 2009
    Review
  18. Article
  19. Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Graham PawelecUniversity of Tübingen Center for Medical Research, ZMF, Waldhörnlestr. 22, 72072 Tubingen, Germany. graham.pawelec@uni-tuebingen.de
Steven G Marsh
The Royal Free Hospital · GBUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunologists working in humans often require panels of tumour cell lines expressing different combinations of HLA alleles and other characteristics. Sources of cell lines are usually large cell banks carrying little immunologically relevant information on the available cells and limited numbers of different lines from the same type of tumour. Access to cells with desired combinations of characteristics is, therefore, difficult. Here, we describe an interactive database of a large collection of melanoma cell lines which have been extensively characterised for HLA genotype and surface expression, oncogene and tumour antigen expression, cytokine secretion, surface molecule expression, adhesion to extracellular matrix components, cytokine gene polymorphisms and other factors of interest to immunologists. This enables investigators to search for cells with particular constellations of HLA alleles, tumour antigens, etc., and then request these from the cell bank. This European Searchable Tumour Cell Line and Data Bank (ESTDAB) was established as a Research Infrastructure of the European Commission. For access to the databank and further details, please go to http://www.ebi.ac.uk/ipd/estdab/ .

Indexed as

Biomarkers, TumorCell Line, TumorDatabases, FactualMelanomaAnimalsHLA AntigensHumansBiomarkers, TumorHLA Antigens

Identifiers

PMID16421722
PMCPMC11030935
OpenAlexW2052813413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.