ArticleJournal of virology2006
The complete genome sequence of herpesvirus papio 2 (Cercopithecine herpesvirus 16) shows evidence of recombination events among various progenitor herpesviruses.
Article in Journal of virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 40 citations in OpenAlex.
- Herpesviruses: overview of systematics, genomic complexity and life cycle.Virology journal · 2025Review
- Primate Simplexviruses Differ in Tropism for Macaque Cells.Microorganisms · 2022Article
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- What do animal models tell us about the role of EBV in the pathogenesis of multiple sclerosis?Frontiers in immunology · 2022Review
- Discovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2.Molecular biology and evolution · 2021Article
- Infectious Disease Risk Across the Growing Human-Non Human Primate Interface: A Review of the Evidence.Frontiers in public health · 2019Review
- Questioning the Extreme Neurovirulence of Monkey B VirusAdvances in virology · 2018Review
- Sequence of the ateline alphaherpesvirus 1 (HVA1) genome.Archives of virology · 2017Article
- Understanding Primate Herpesviruses.Journal of emerging diseases and virology · 2017Article
- Vaginal Dysbiosis from an Evolutionary Perspective.Scientific reports · 2016Article
- Genome sequence of a pathogenic isolate of monkey B virus (species Macacine herpesvirus 1).Archives of virology · 2014Article
- Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).Comparative medicine · 2014Article
- Evolutionary origins of human herpes simplex viruses 1 and 2.Molecular biology and evolution · 2014Article
- A single viral gene determines lethal cross-species neurovirulence of baboon herpesvirus HVP2.Virology · 2014Article
- Analysis of the genome of leporid herpesvirus 4.Virology · 2012Article
- RNA binding properties of the US11 protein from four primate simplexviruses.Virology journal · 2011Article
- The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms.Annals of the New York Academy of Sciences · 2011Review
- Article
- Herpesvirus systematics.Veterinary microbiology · 2010Article
- Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.Virology journal · 2009Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have sequenced the entire genome of herpesvirus papio 2 (HVP-2; Cercopithecine herpesvirus 16) strain X313, a baboon herpesvirus with close homology to other primate alphaherpesviruses, such as SA8, monkey B virus, and herpes simplex virus (HSV) type 1 and type 2. The genome of HVP-2 is 156,487 bp in length, with an overall GC content of 76.5%. The genome organization is identical to that of the other members of the genus Simplexvirus, with a long and a short unique region, each bordered by inverted repeats which end with an "a" sequence. All of the open reading frames detected in this genome were homologous and colinear with those of SA8 and B virus. The HSV gene RL1 (gamma(1)34.5; neurovirulence factor) is not present in HVP-2, as is the case for SA8 and B virus. The HVP-2 genome is 85% homologous to its closest relative, SA8. However, segment-by-segment bootstrap analysis of the genome revealed at least two regions that display closer homology to the corresponding sequences of B virus. The first region comprises the UL41 to UL44 genes, and the second region is located within the UL36 gene. We hypothesize that this localized and defined shift in homology is due to recombination events between an SA8-like progenitor of HVP-2 and a herpesvirus species more closely related to the B virus. Since some of the genes involved in these putative recombination events are determinants of virulence, a comparative analysis of their function may provide insight into the pathogenic mechanism of simplexviruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.