Evidence map›Paper›PMID 16414360›Full record

ArticleSurvey of ophthalmology

Primary testicular and intraocular lymphomas: two case reports and a review of the literature.

Dana J Wallace, Chandra R Altemare, De Fen Shen, Marc D deSmet, Ronald R Buggage, Robert B Nussenblatt, Chi-Chao Chan

Open access · greenAbstract readCase Reports
In one paragraph

Article in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Dana J WallaceNational Eye Institute/NIH, Bldg. 10, 10 Center Drive, Bethesda, MD 20892, USA.
Chandra R Altemare
De Fen Shen
Marc D deSmet
Ronald R Buggage
Robert B Nussenblatt
Chi-Chao Chan
National Eye Institute · USUniversity of Amsterdam · NL

Funding

Molecular And Immunopathology Of Ocular DiseasesZ01EY000222 · NEI · NATIONAL EYE INSTITUTE · PI CHAN, CHI-CHAO · 1986 to 2008
$3.6M
Diagnosis And Treatment Of Ocular Inflammatory Disease (uveitis)Z01EY000356 · NEI · NATIONAL EYE INSTITUTE · PI NUSSENBLATT, ROBERT B. · 2000 to 2008
$986k
Single Nucleotide Polymorphisms In Primary Intraocular LZ01EY000375 · NEI · NATIONAL EYE INSTITUTE · PI NUSSENBLATT, ROBERT B. · 2001 to 2008
$182k
Intramural NIH HHS Z01 EY000222
6 · The paper itself

Abstract

Testicular lymphoma is a rare neoplasm of the testis that is most commonly seen in older patients. It metastasizes preferentially to extranodal sites, including the skin, central nervous system, Waldeyer ring, contralateral testis, and lung. Two case reports of patients with a history of testicular lymphoma who developed involvement of the vitreous and retina are presented. These are interesting cases as the testis, central nervous system, and eye are all immune privileged organs, which may account for occurrence of disease in these sites. Histopathologic examination of diagnostic vitrectomy specimens from both cases showed atypical lymphoid cells with immunoglobulin heavy chain (IgH) gene rearrangements, consistent with the diagnosis of intraocular B-cell lymphoma. The results of a literature review of all reports of ocular involvement with testicular lymphoma are discussed. Patients with testicular lymphoma are at risk for relapse, particularly in the central nervous system. Clinicians should be suspicious for intraocular lymphoma in patients with a history of testicular lymphoma who present with vitritis or retinal lesions.

Indexed as

AgedAntineoplastic AgentsDiagnosis, DifferentialEye NeoplasmsFluorescein AngiographyFundus OculiHumansLymphoma, B-CellMaleMiddle AgedRetinal NeoplasmsTesticular NeoplasmsVitrectomyVitreous BodyAntineoplastic Agents

Identifiers

PMID16414360
PMCPMC1930146
OpenAlexW2043749894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.