ArticleNucleic acids research2006
Cockayne syndrome group B protein has novel strand annealing and exchange activities.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- Role of Cockayne Syndrome Group B Protein in Replication Stress: Implications for Cancer Therapy.International journal of molecular sciences · 2022Review
- Review
- Current and emerging roles of Cockayne syndrome group B (CSB) protein.Nucleic acids research · 2021Review
- Review
- Fine-tuning of the replisome: Mcm10 regulates fork progression and regression.Cell cycle (Georgetown, Tex.) · 2019Review
- Mechanistic insights into the regulation of transcription and transcription-coupled DNA repair by Cockayne syndrome protein B.Nucleic acids research · 2018Article
- Article
- NAP1L1 accelerates activation and decreases pausing to enhance nucleosome remodeling by CSB.Nucleic acids research · 2017Article
- ERCC6 dysfunction presenting as progressive neurological decline with brain hypomyelination.American journal of medical genetics. Part A · 2014Article
- DNA repair mechanisms in dividing and non-dividing cells.DNA repair · 2013Review
- Mammalian transcription-coupled excision repair.Cold Spring Harbor perspectives in biology · 2013Review
- ATP-dependent chromatin remodeling by Cockayne syndrome protein B and NAP1-like histone chaperones is required for efficient transcription-coupled DNA repair.PLoS genetics · 2013Article
- Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation.Nucleic acids research · 2012Article
- Unwinding and rewinding: double faces of helicase?Journal of nucleic acids · 2012Article
- Downregulation of Cockayne syndrome B protein reduces human 8-oxoguanine DNA glycosylase-1 expression and repair of UV radiation-induced 8-oxo-7,8-dihydro-2'-deoxyguanine.Cancer science · 2011Article
- Involvement of oxidatively damaged DNA and repair in cancer development and aging.American journal of translational research · 2010Article
- Distinct roles of RECQ1 in the maintenance of genomic stability.DNA repair · 2010Review
- UV-induced association of the CSB remodeling protein with chromatin requires ATP-dependent relief of N-terminal autorepression.Molecular cell · 2010Article
- Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity.Nature reviews. Genetics · 2009Review
- Nucleic acid binding activity of human Cockayne syndrome B protein and identification of Ca(2+) as a novel metal cofactor.Journal of molecular biology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, severe neurological abnormalities and prageroid symptoms. The CS complementation group B (CSB) protein is involved in UV-induced transcription coupled repair (TCR), base excision repair and general transcription. CSB also has a DNA-dependent ATPase activity that may play a role in remodeling chromatin in vivo. This study reports the novel finding that CSB catalyzes the annealing of complementary single-stranded DNA (ssDNA) molecules with high efficiency, and has strand exchange activity. The rate of CSB-catalyzed annealing of complementary ssDNA is 25-fold faster than the rate of spontaneous ssDNA annealing under identical in vitro conditions and the reaction occurs with a high specificity in the presence of excess non-homologous ssDNA. The specificity and intrinsic nature of the reaction is also confirmed by the observation that it is stimulated by dephosphorylation of CSB, which occurs after UV-induced DNA damage, and is inhibited in the presence of ATPgammaS. Potential roles of CSB in cooperation with strand annealing and exchange activities for TCR and homologous recombination are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.