ArticleDevelopment (Cambridge, England)2006
bZIP transcription factor interactions regulate DIF responses in Dictyostelium.
Article in Development (Cambridge, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- The polymorphic proteins TgrB1 and TgrC1 function as a ligand-receptor pair inJournal of cell science · 2017Article
- Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria inBiology open · 2017Article
- Glutathione S-transferase 4 is a putative DIF-binding protein that regulates the size of fruiting bodies inBiochemistry and biophysics reports · 2016Article
- The GATA transcription factor gene gtaG is required for terminal differentiation in Dictyostelium.Journal of cell science · 2016Article
- Secreted Cyclic Di-GMP Induces Stalk Cell Differentiation in the Eukaryote Dictyostelium discoideum.Journal of bacteriology · 2016Review
- The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes.Molecular biology of the cell · 2015Article
- c-di-GMP induction of Dictyostelium cell death requires the polyketide DIF-1.Molecular biology of the cell · 2015Article
- Article
- Cell signaling during development of Dictyostelium.Developmental biology · 2014Review
- Defects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum.Biology open · 2014Article
- Article
- Transcriptional repression by a bZIP protein regulates Dictyostelium prespore differentiation.PloS one · 2012Article
- An orthologue of the Myelin-gene Regulatory Transcription Factor regulates Dictyostelium prestalk differentiation.The International journal of developmental biology · 2012Article
- BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium.Developmental biology · 2011Article
- DIF-1 regulates Dictyostelium basal disc differentiation by inducing the nuclear accumulation of a bZIP transcription factor.Developmental biology · 2011Article
- A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.Developmental biology · 2011Article
- Cell type-specific filamin complex regulation by a novel class of HECT ubiquitin ligase is required for normal cell motility and patterning.Development (Cambridge, England) · 2011Article
- A simple mechanism for complex social behavior.PLoS biology · 2011Article
- Article
- Dictyostelium finds new roles to model.Genetics · 2010Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The signalling molecule DIF-1 is required for normal cell fate choice and patterning in Dictyostelium. To understand how these developmental processes are regulated will require knowledge of how cells receive and respond to the DIF-1 signal. Previously, we have described a bZIP transcription factor, DimA, which is required for cells to respond to DIF-1. However, it was unknown whether DimA activity is required to activate the DIF response pathway in certain cells or is a component of the response pathway itself. In this study, we describe the identification of a DimA-related bZIP transcription factor, DimB. Rapid changes in the subcellular localisation of both DimA and DimB in response to DIF-1 suggest that they are directly downstream of the DIF-1 signal. Genetic and biochemical interactions between DimA and DimB provides evidence that their ability to regulate diverse targets in response to DIF-1 is partly due to their ability to form homo- and heterodimeric complexes. DimA and DimB are therefore direct regulators of cellular responses to DIF-1.
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