ArticleArchives of disease in childhood. Fetal and neonatal edition2006
Predicting successful extubation of very low birthweight infants.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Utility of Spontaneous Breathing Trial (SBT) Using ET-CPAP, in Predicting Extubation Failure in Neonates
Integrated Prediction of Extubation Outcome by the Spontaneous Breathing Trial in Newborn Infants
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Peri-extubation settings in preterm neonates: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2024Pooled it
- Predictors of extubation failure in newborns: a systematic review and meta-analysis.Italian journal of pediatrics · 2023Pooled it
- Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants.The Cochrane database of systematic reviews · 2016Pooled it
- Extubation from low-rate intermittent positive airways pressure versus extubation after a trial of endotracheal continuous positive airways pressure in intubated preterm infants.The Cochrane database of systematic reviews · 2000Pooled it
- Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation.The Journal of pediatrics · 2017Trial
- Accuracy of lung ultrasound in predicting successful extubation in preterm infants born ≤ 25 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Predicting extubation failure in neonates: The role of lung ultrasound and corrected gestational age in safe weaning in the NICU.European journal of pediatrics · 2025Observational
- Ventilator variables predicting extubation readiness in extremely premature infants with prolonged mechanical ventilation: A retrospective observational study.Pediatric pulmonology · 2024Observational
- Article
- Diaphragmatic electromyography in infants: an overview of possible clinical applications.Pediatric research · 2024Review
- Predictive factors for extubation success in very low and extremely low birth weight preterm infants.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023Article
- Accuracy of the spontaneous breathing trial using a combined CPAP + PSV model to predict extubation outcomes in very preterm infants.BMC pediatrics · 2022Article
- Diaphragmatic electromyography during a spontaneous breathing trial to predict extubation failure in preterm infants.Pediatric research · 2022Article
- Predictors of extubation success: a population-based study of neonates below a gestational age of 26 weeks.BMJ paediatrics open · 2022Article
- Risk Factors of Extubation Failure in Intubated Preterm Infants at a Tertiary Care Hospital in Oman.Sultan Qaboos University medical journal · 2022Article
- Can Fraction of Inspired Oxygen Predict Extubation Failure in Preterm Infants?Children (Basel, Switzerland) · 2022Article
- Accuracy of Spontaneous Breathing Trial Using ET-CPAP in Predicting Successful Extubation of Neonates.Cureus · 2021Article
- Assessment of Extubation Readiness Using Spontaneous Breathing Trials in Extremely Preterm Neonates.JAMA pediatrics · 2020Article
- Effects of an extubation readiness test protocol at a tertiary care fully outborn neonatal intensive care unit.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2019Article
- Extubation from high-frequency oscillatory ventilation in extremely low birth weight infants: a prospective observational study.BMJ paediatrics open · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the accuracy of three tests used to predict successful extubation of preterm infants. STUDY
designMechanically ventilated infants with birth weight <1250 g and considered ready for extubation were changed to endotracheal continuous positive airway pressure (ET CPAP) for three minutes. Tidal volumes, minute ventilation (V e), heart rate, and oxygen saturation were recorded before and during ET CPAP. Three tests of extubation success were evaluated: (a) expired V e during ET CPAP; (b) ratio of V e during ET CPAP to V e during mechanical ventilation (V e ratio); (c) the spontaneous breathing test (SBT)-the infant passed this test if there was no hypoxia or bradycardia during ET CPAP. The clinical team were blinded to the results, and all infants were extubated. Extubation failure was defined as reintubation within 72 hours of extubation.
resultsFifty infants were studied and extubated. Eleven (22%) were reintubated. The SBT was the most accurate of the three tests, with a sensitivity of 97% and specificity of 73% and a positive and negative predictive value for extubation success of 93% and 89% respectively.
conclusionThe SBT used just before extubation of infants <1250 g may reduce the number of extubation failures. Further studies are required to establish whether the SBT can be used as the primary determinant of an infant's readiness for extubation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.