Evidence map›Paper›PMID 16409650›Full record

ArticleEpidemiology and infection2006

Crohn's disease in people exposed to clinical cases of bovine paratuberculosis.

P H Jones, T B Farver, B Beaman, B Cetinkaya, K L Morgan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. The zoonotic potential of Mycobacterium avium spp. paratuberculosis: a systematic review.Canadian journal of public health = Revue canadienne de sante publique
    Pooled it
  3. Article
  4. Translational gastroenterology and hepatology · 2023
    Review
  5. Review
  6. Anti-Frontline gastroenterology · 2021
    Article
  7. Review
  8. Article
  9. Mycobacterium paratuberculosis as a cause of Crohn's disease.Expert review of gastroenterology & hepatology · 2015
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. In the search of a cause of Crohn's disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

P H JonesDivision of Farm Animal Science, School of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol, UK. p.h.jones@bris.ac.uk
T B Farver
B Beaman
B Cetinkaya
K L Morgan
University of California, Davis · USUniversity of Bristol · GBUniversity of Liverpool · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mycobacterium avium subspecies paratuberculosis (Map), the cause of ruminant paratuberculosis, has been proposed as the causative agent of Crohn's disease. The objective of this study was to determine whether exposure to clinical cases of bovine paratuberculosis was a risk factor for Crohn's disease. A questionnaire was sent to dairy farmers living on premises where the occurrence or absence of clinical cases of bovine paratuberculosis had previously been determined. The prevalence of Crohn's disease was found to be similar to that reported in other studies in the United Kingdom and showed no association with bovine paratuberculosis. There was, however, a univariate association with geographical region. Ulcerative colitis showed univariate associations with age, frequency of contact with cattle and with smoking. The results do not support the hypothesis that Map plays a causative role in the aetiology of Crohn's disease.

Indexed as

Cattle DiseasesAdultAgedAnimalsCattleCrohn DiseaseDairyingData CollectionEnvironmental ExposureEpidemiologic StudiesFemaleHumansMaleMiddle AgedMycobacterium avium subsp. paratuberculosisParatuberculosis

Identifiers

PMID16409650
PMCPMC2870362
OpenAlexW2034736622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.