Evidence map›Paper›PMID 16407381›Full record

ArticleGut2006

Anticipating disaster: the genetics of familial pancreatic cancer.

M M Lerch

Open access · bronzeAbstract readComment
In one paragraph

Article in Gut, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Incidence of pancreatic cancer in Greenland 2000-2010.International journal of circumpolar health · 2012
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

M M LerchDepartment of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt-Universität Greifswald, Friedrich Loeffler Str 23A, D-17484 Greifswald, Germany. lerch@uni-greifswald.de
Universität Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To be born into a family with familial pancreatic cancer, an inheritable, autosomal dominant disorder, has various implications for an individual's life--and none is fortunate. The prospects just turned even darker because of "anticipation", the phenomenon that successive generations are affected by an inheritable disorder at a progressively earlier age. An up to date study shows that "anticipation" is also operative in familial pancreatic cancer, meaning that affected children die approximately 10 years earlier than their affected parents.

Indexed as

Anticipation, GeneticAgedAge of OnsetGenetic Predisposition to DiseaseHumansMiddle AgedNeoplastic Syndromes, HereditaryPancreatic Neoplasms

Identifiers

PMID16407381
PMCPMC1856499
OpenAlexW2125028014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.