Evidence map›Paper›PMID 16407380›Full record

ArticleGut2006

To be or not to be--an incretin or enterogastrone?

M Horowitz, M A Nauck

Registry-linked trialAbstract readComment
In one paragraph

Article in Gut, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02308254 (Effects of Lixisenatide on Gastric Emptying, Glycaemia and 'Postprandial' Blood Pressure in Type 2 Diabetes and Healthy Subjects.), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02308254 phase1 / phase2unknown statusnot on this mapstarted 2013, after this paper: background citation

Effects of Lixisenatide on Gastric Emptying, Glycaemia and 'Postprandial' Blood Pressure in Type 2 Diabetes and Healthy Subjects.

TypeinterventionalSponsorRoyal Adelaide HospitalRan2013 to 2016Enrolled30ConditionsDiabetes Mellitus, GastroparesisArmsLixisenatide, Placebo
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Peripheral neural targets in obesity.British journal of pharmacology · 2012
    Review
  8. Review
  9. Sensing via intestinal sweet taste pathways.Frontiers in neuroscience · 2011
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

M HorowitzUniversity of Adelaide, Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, South Australia 5005, Australia. michael.horowitz@adelaide.edu.au
M A Nauck

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucagon-like peptide 1 does not comfortably fulfil the criterion of a gut derived factor responsible for an enhanced meal related insulin response; it appears logical to add the definition of a "physiological incretin hormone".

Indexed as

Blood GlucoseGastric EmptyingGastrointestinal MotilityGlucagon-Like Peptide 1HumansInsulinInsulin SecretionBlood GlucoseGlucagon-Like Peptide 1Insulin

Identifiers

PMID16407380
PMCPMC1856501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.