Evidence map›Paper›PMID 16400183›Full record

ArticleEukaryotic cell2006

Heterologous expression of an Entamoeba histolytica chitin synthase in Saccharomyces cerevisiae.

Katrina L Van Dellen, Dorota A Bulik, Charles A Specht, Phillips W Robbins, John C Samuelson

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katrina L Van DellenDepartment of Molecular and Cell Biology, Boston University Goldman School of Dental Medicine, 715 Albany St., Evans 426, Boston, Massachusetts 02118, USA.
Dorota A Bulik
Charles A Specht
Phillips W Robbins
John C Samuelson
Boston University · US

Funding

ROBBINS Glycosylation and Glycosidases-Cell and Molecular BiologyR01GM031318 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SAMUELSON, JOHN C. · 1985 to 2011
$4.1M
THREE LECTIN MODEL OF AMEBIC ENCYSTATION AND EXCYSTATIONR01AI044070 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SAMUELSON, JOHN C. · 2000 to 2010
$4.0M
PROTEIN GLYCOSYLATION - CELLULAR AND MOLECULAR BIOLOGYR37GM031318 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROBBINS, PHILLIPS W · 1988 to 1997
–
NIAID NIH HHS AI44070NIAID NIH HHS R01 AI044070NIGMS NIH HHS GM31318NIGMS NIH HHS R01 GM031318
6 · The paper itself

Abstract

Chitin in the cyst wall of Entamoeba histolytica is made by two chitin synthases (Chs), one of which is unique (EhCHS-1) and one of which resembles those of insects and nematodes (EhCHS-2). EhCHS-1 is deposited chitin in the lateral wall of transformed Saccharomyces cerevisiae Chs mutants, independent of accessory proteins (Chs4p to Chs7p) required by yeast Chs3p.

Indexed as

AnimalsCatalysisChitinChitin SynthaseEntamoeba histolyticaGene ExpressionMutationPhylogenySaccharomyces cerevisiaeChitinChitin Synthase

Identifiers

PMID16400183
PMCPMC1360259
OpenAlexW2107183837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.