ArticleThe Journal of clinical investigation2006
Delving deeper into MALT lymphoma biology.
Article in The Journal of clinical investigation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- A Phase II Trial of the Bruton Tyrosine-Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Relapsed/Refractory Waldenström Macroglobulinemia.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021Trial
- Significance of Notch Signaling in Salivary Gland Development and Diseases.Journal of clinical medicine · 2025Review
- [Characteristics of Gastric Mucosa-associated Lymphoid Tissue Lymphoma in Korea].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024Review
- Primary pulmonary mucosa-associated lymphoid tissue lymphoma: A case report.Radiology case reports · 2022Article
- Review
- Review
- Impact of the microenvironment on the pathogenesis of mucosa-associated lymphoid tissue lymphomas.World journal of gastrointestinal oncology · 2022Review
- Review
- Lessons to cancer from studies of leukemia and hematopoiesis.Frontiers in cell and developmental biology · 2022Review
- The clinical potential of circulating immune cell counts in primary gastric lymphoma.Journal of gastrointestinal oncology · 2021Article
- The Bacterial Microbiota of Gastrointestinal Cancers: Role in Cancer Pathogenesis and Therapeutic Perspectives.Clinical and experimental gastroenterology · 2020Review
- Clinical aspects of malt lymphomas.Current hematologic malignancy reports · 2014Review
- A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.Science (New York, N.Y.) · 2014Article
- Gastric MALT lymphoma: old and new insights.Annals of gastroenterology · 2014Review
- Lymphoproliferative lung disorders: clinicopathological aspects.European respiratory review : an official journal of the European Respiratory Society · 2013Review
- The costimulatory immunogen LPS induces the B-Cell clones that infiltrate transplanted human kidneys.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Genomic profiles of MALT lymphomas: variability across anatomical sites.Haematologica · 2011Article
- Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Article
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mucosa-associated lymphoid tissue (MALT) lymphomas can arise in a variety of extranodal sites. Interestingly, at least 3 different, apparently site-specific, chromosomal translocations, all affecting the NF-kappaB pathway, have been implicated in the development and progression of MALT lymphoma. The most common is the translocation t(11;18)(q21;q21), which results in a fusion of the cIAP2 region on chromosome 11q21 with the MALT1 gene on chromosome 18q21 and is present in more than one-third of cases. The frequency of this translocation is site-related: common in the gastrointestinal tract and lung, rare in conjunctiva and orbit, and almost absent in salivary glands, thyroid, liver, and skin. In this issue of the JCI, Hu et al. add to our understanding of the molecular consequences of this translocation, showing that its fusion product, cIAP2-MALT1, may concomitantly contribute to lymphomagenesis both as a tumor suppressor gene and as an oncogene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.