Evidence map›Paper›PMID 16395320›Full record

ArticleInternational journal of impotence research

Mediterranean diet improves erectile function in subjects with the metabolic syndrome.

K Esposito, M Ciotola, F Giugliano, M De Sio, G Giugliano, M D'armiento, D Giugliano

2 registry-linked trialsAbstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 6 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04349059 narecruitingnot on this map

The Impact of a Plant-Based Diet Versus an Animal-Based Diet on Erectile Function in Healthy Men With Normal Erectile Function: The ERECTION Study

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2026Enrolled46ConditionsErectile DysfunctionArmsAnimal based diet, Plant based diet
NCT05632367 completednot on this map

The Effects of Nutritional Characteristics of Obese Men and Women on Their Sexual Functions.

Typeobservational_patient_registrySponsorIstanbul UniversityRan2015 to 2015Enrolled185ConditionsSexual Dysfunction, Mediterranean Diet, Aphrodisiac Foods, Obesity
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 6 syntheses or guidelines pooled it, 161 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

K EspositoDivision of Metabolic Diseases, University of Naples SUN, Piazza Miraglia, Naples, Italy. katherine.esposito@unina2.it
M Ciotola
F Giugliano
M De Sio
G Giugliano
M D'armiento
D Giugliano
University of Naples Federico II · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men with the metabolic syndrome demonstrate an increased prevalence of erectile dysfunction (ED). In the present study, we tested the effect of a Mediterranean-style diet on ED in men with the metabolic syndrome. Men were identified in our database of subjects participating in controlled trials evaluating the effect of lifestyle changes and were included if they had a diagnosis of ED associated with a diagnosis of metabolic syndrome, complete follow-up in the study trial, and intervention focused mainly on dietary changes. Sixty-five men with the metabolic syndrome met the inclusion/exclusion criteria; 35 out of them were assigned to the Mediterranean-style diet and 30 to the control diet. After 2 years, men on the Mediterranean diet consumed more fruits, vegetables, nuts, whole grain, and olive oil as compared with men on the control diet. Endothelial function score and inflammatory markers (C-reactive protein) improved in the intervention group, but remained stable in the control group. There were 13 men in the intervention group and two in the control group (P=0.015) that reported an IIEF score of 22 or higher. Mediterranean-style diet rich in whole grain, fruits, vegetables, legumes, walnut, and olive oil might be effective per se in reducing the prevalence of ED in men with the metabolic syndrome.

Indexed as

Diet, MediterraneanAdultC-Reactive ProteinEndothelium, VascularErectile DysfunctionHumansMaleMetabolic SyndromeMiddle AgedPenile ErectionTreatment OutcomeC-Reactive Protein

Identifiers

PMID16395320
OpenAlexW2063316820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.