ReviewEnvironmental health perspectives2006
A case for revisiting the safety of pesticides: a closer look at neurodevelopment.
Review in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed.
- Brain Abnormalities in Children Exposed Prenatally to the Pesticide Chlorpyrifos.JAMA neurology · 2025Article
- Prenatal pyrethroid exposure, placental gene network modules, and neonatal neurobehavior.International journal of hygiene and environmental health · 2025Article
- Sperm abnormality and infertility in male mice treated with the recommended dose of dimethoate and its double.Open veterinary journal · 2023Article
- A review on the pesticides in coffee: Usage, health effects, detection, and mitigation.Frontiers in public health · 2022Review
- Occurrence of multiclass pesticide residues in tomato samples collected from different markets of Iran.Journal of environmental health science & engineering · 2018Article
- The Impact of Prenatal Organophosphate Pesticide Exposures on Thai Infant Neurodevelopment.International journal of environmental research and public health · 2017Article
- Developmental neurotoxicity of succeeding generations of insecticides.Environment international · 2017Review
- Organochlorine pesticide residues in dried cocoa beans obtained from cocoa stores at Ondo and Ile-Ife, Southwestern Nigeria.Toxicology reports · 2017Article
- Dissipation kinetics and effect of processing on imidacloprid and its metabolites in cardamom (Elettaria cardamomum Maton).Environmental monitoring and assessment · 2016Article
- Exposure to sublethal concentrations of a pesticide or predator cues induces changes in brain architecture in larval amphibians.Oecologia · 2015Article
- Neurobehavioral effects of exposure to organophosphates and pyrethroid pesticides among Thai children.Neurotoxicology · 2015Article
- Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism.Molecular autism · 2015Article
- Prenatal organophosphates exposure alternates the cleavage plane orientation of apical neural progenitor in developing neocortex.PloS one · 2014Article
- Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos?Environmental toxicology and pharmacology · 2013Article
- Dissipation kinetics and assessment of processing factor for chlorpyrifos and lambda-cyhalothrin in cardamom.Environmental monitoring and assessment · 2013Article
- Article
- Chlorpyrifos and neurodevelopmental effects: a literature review and expert elicitation on research and policy.Environmental health : a global access science source · 2012Review
- Pesticide exposure and child neurodevelopment: summary and implications.Workplace health & safety · 2012Article
- Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro.Neurotoxicology and teratology · 2012Article
- Chlorpyrifos exposure and urban residential environment characteristics as determinants of early childhood neurodevelopment.American journal of public health · 2011Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The quality and quantity of the data about the risk posed to humans by individual pesticides vary considerably. Unlike obvious birth defects, most developmental effects cannot be seen at birth or even later in life. Instead, brain and nervous system disturbances are expressed in terms of how an individual behaves and functions, which can vary considerably from birth through adulthood. In this article I challenge the protective value of current pesticide risk assessment strategies in light of the vast numbers of pesticides on the market and the vast number of possible target tissues and end points that often differ depending upon timing of exposure. Using the insecticide chlorpyrifos as a model, I reinforce the need for a new approach to determine the safety of all pesticide classes. Because of the uncertainty that will continue to exist about the safety of pesticides, it is apparent that a new regulatory approach to protect human health is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.