Evidence map›Paper›PMID 16392005›Full record

ArticleCurrent microbiology2006

Gene expression profiling of intrinsic thermotolerance in Escherichia coli.

S Marvin Friedman, Mohammed Hossain, Tal H Hasson, Akira Kawamura

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S Marvin FriedmanDepartment of Biological Sciences, Hunter College of The City University of New York, 695 Park Avenue, New York, NY 10021, USA. friedman@genectr.hunter.cuny.edu
Mohammed Hossain
Tal H Hasson
Akira Kawamura

Funding

NCRR NIH HHS RR-03037
6 · The paper itself

Abstract

DNA microarrays were employed to compare gene expression in a thermotolerant, nalidixic acid-resistant mutant of Escherichia coli with that of the parental strain. When grown at 37 degrees C, up-regulated genes in the mutant included those coding for multiple antibiotic resistance proteins and enzymes for the degradation of small molecules, whereas among the down-regulated genes were those coding for fimbrial, flagellar, and outer membrane proteins as well as sigma 38. When the mutant grown at 42 degrees C was compared to the mutant grown at 37 degrees C, enhanced expression of several genes coding for flagellar proteins was detected. Reverse transcriptase-polymerase chain reaction analysis of selected genes confirmed results obtained with microarrays.

Indexed as

Gene Expression ProfilingGene Expression Regulation, BacterialHot TemperatureAdaptation, PhysiologicalAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsMutationNalidixic AcidOligonucleotide Array Sequence AnalysisReverse Transcriptase Polymerase Chain ReactionRNA, BacterialRNA, MessengerAnti-Bacterial AgentsEscherichia coli ProteinsNalidixic AcidRNA, BacterialRNA, Messenger

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.