ReviewExperientia1992
Mammalian heat shock protein families. Expression and functions.
Review in Experientia, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 105 citations in OpenAlex.
- From Systemic Stress to Ovarian Failure: Heat Stress-Induced Infertility in Pigs as a Model for Reproductive Dysfunction.Current issues in molecular biology · 2026Review
- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Systemic and ovarian impacts of heat stress in the porcine model.Reproduction (Cambridge, England) · 2024Review
- Porcine endometrial heat shock proteins are differentially influenced by pregnancy status, heat stress, and altrenogest supplementation during the peri-implantation period.Journal of animal science · 2022Article
- TRIM11 cooperates with HSF1 to suppress the anti-tumor effect of proteotoxic stress drugs.Cell cycle (Georgetown, Tex.) · 2019Article
- Parainflammation, chronic inflammation, and age-related macular degeneration.Journal of leukocyte biology · 2015Review
- Heat shock protein expression analysis in canine osteosarcoma reveals HSP60 as a potentially relevant therapeutic target.Cell stress & chaperones · 2013Article
- Hyperglycaemia and oxidative stress upregulate HSP60 & HSP70 expression in HeLa cells.SpringerPlus · 2013Article
- Responses of muscle mass, strength and gene transcripts to long-term heat stress in healthy human subjects.European journal of applied physiology · 2011Article
- Heat shock memory in preimplantation mouse embryos.Fertility and sterility · 2010Article
- Osmoadaptation of Mammalian cells - an orchestrated network of protective genes.Current genomics · 2007Article
- Heat shock proteins, end effectors of myocardium ischemic preconditioning?Cell stress & chaperones · 2006Article
- Heat shock proteins in immune reactions.Folia microbiologica · 1999Review
- Induction of heat shock protein expression in cervical epithelial cells by human semen.Infectious diseases in obstetrics and gynecology · 1999Article
- Expression of heat shock protein 70 blocks thymic differentiation of T cells in transgenic mice.Immunology · 1998Article
- Heller syndrome in a pre-school boy. Proposed medical evaluation and hypothesized pathogenesis.European child & adolescent psychiatry · 1996Article
- Heat shock proteins HSP25, HSP60, HSP72, HSP73 in isoosmotic cortex and hyperosmotic medulla of rat kidney.Pflugers Archiv : European journal of physiology · 1996Article
- Porcine 5S rRNA genes map to 14q23 revealing syntenic relation to human HSPA6- and 7.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Overexpression and abnormal modification of the stress proteins alpha B-crystallin and HSP27 in Alexander disease.The American journal of pathology · 1993Article
- Heat shock proteins. Introduction.Experientia · 1992Review
- Heat shock proteins in autoimmune disease. From causative antigen to specific therapy?Experientia · 1992Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When prokaryotic or eukaryotic cells are submitted to a transient rise in temperature or to other proteotoxic treatments, the synthesis of a set of proteins called the heat shock proteins (hsp) is induced. The structure of these proteins has been highly conserved during evolution. The signal leading to the transcriptional activation of the corresponding genes is the accumulation of denatured and/or aggregated proteins inside the cells after stressful treatment. The expression of a subset of hsp is also induced during early embryogenesis and many differentiation processes. Two different functions have been ascribed to hsp: a molecular chaperone function: chaperones mediate the folding, assembly or translocation across the intracellular membranes of other polypeptides, and a role in protein degradation: some of the essential components of the cytoplasmic ubiquitin-dependent degradative pathway are hsp. These functions of hsp are essential in every living cell. They are required for repairing the damage resulting from stress.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.