ArticleJournal of clinical microbiology2006
Viridans streptococci isolated by culture from blood of cancer patients: clinical and microbiologic analysis of 50 cases.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 130 citations in OpenAlex.
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- Clinical and genomic features of mitis group streptococcal bacteremia in patients with febrile neutropenia.BMC infectious diseases · 2026Article
- Abiotrophia defectiva spondylodiscitis: case report and literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Encapsulation of Disease-Causing and Commensal Mitis Group Non-Pneumococcal Streptococci.Pathogens (Basel, Switzerland) · 2025Article
- Ceftriaxone-resistant viridans streptococci bacteraemia among patients treated at a large comprehensive cancer care centre: a retrospective eighteen-year study.JAC-antimicrobial resistance · 2024Article
- Streptococcus taonis sp. nov., a novel bacterial species isolated from a blood culture of a patient.Archives of microbiology · 2024Article
- Peritoneal Dialysis-associated Peritonitis Due to Streptococcus oralis Three Weeks after Peritoneal Dialysis Initiation.Internal medicine (Tokyo, Japan) · 2024Article
- Performance assessment of the Bruker Biotyper MALDI-TOF MS for the identification of difficult-to-identify viridans group streptococci.Journal of clinical microbiology · 2023Article
- Clinical and microbiological characteristics of polymicrobial bacteremia: a retrospective, multicenter study.Infection · 2022Review
- Peritoneal Dialysis-Related Peritonitis Caused by Streptococcus oralis.Internal medicine (Tokyo, Japan) · 2021Review
- Treatment refractoryBMJ case reports · 2021Article
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- Effects of Expression ofFrontiers in microbiology · 2021Article
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- Species-Specific Identification of Streptococcus based on DNA Marker in 16S-23S rDNA Internal Transcribed Spacer.Current microbiology · 2020Article
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- Viridans streptococcus peritonitis in peritoneal dialysis: clinical characteristics and comparison with concurrent polymicrobial infection.BMC nephrology · 2018Article
- Identification of Streptococcus mitis321A vaccine antigens based on reverse vaccinology.Molecular medicine reports · 2018Article
- Post-Obstructive Pneumonia in Patients with Cancer: A Review.Infectious diseases and therapy · 2018Review
- Diversity of Integrative and Conjugative Elements of Streptococcus salivarius and Their Intra- and Interspecies Transfer.Applied and environmental microbiology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Clinical and microbiologic studies of 50 cases of viridans streptococcal bacteremia in cancer patients were performed. The bacteria were identified to species level by sequencing analysis of the 16S rRNA gene. At least nine Streptococcus spp. were found, including S. mitis (25 strains, 50.0% of 50); currently unnamed Streptococcus spp. (11 strains); S. parasanguis (five strains); S. anginosus (three strains); S. salivarius (two strains); and one strain each of S. gordonii, S. sanguis, S. sobrinus, and S. vestibularis. There were no S. oralis strains. Among 11 antibiotics of nine classes tested, no resistance to vancomycin, linezolid, or quinupristin-dalfopristin was seen. Resistance to penicillin (MIC, 4 to 12 mug/ml) was noted only among S. mitis strains (28.0%, 7/25) and not non-S. mitis strains (0/25) (P = 0.004). Significantly more S. mitis strains than non-S. mitis strains were resistant to fluoroquinolones and to > or =3 classes of antibiotics. Isolation of quinolone-resistant organisms was associated with the prior usage of quinolones (P = 0.002). Quantitative blood cultures showed that the strains resistant to levofloxacin or gatifloxacin were associated with higher colony counts than were their corresponding nonresistant strains. The young and elderly patients also had higher levels of bacteremia caused predominantly by S. mitis. Septic shock was present in 17 (34.0% of 50) patients, and 13 of those cases were caused by S. mitis (P = 0.007). These results suggest that S. mitis is the most common cause of viridans streptococcal bacteremia in cancer patients and is more resistant to antibiotics than other species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.