ArticleJournal of clinical microbiology2006
Establishing a method of inoculum preparation for susceptibility testing of Trichophyton rubrum and Trichophyton mentagrophytes.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Do essential oils from plants occurring in the Brazilian Caatinga biome present antifungal potential against dermatophytoses? A systematic review.Applied microbiology and biotechnology · 2021Pooled it
- Probiotic Apilactobacillus Kunkeei EABW06 from Beeswax Microbiota: A Candidate for Functional Dairy Foods.Probiotics and antimicrobial proteins · 2026Article
- Mycological Survey of Fungal Carriage in Cats and Their Owners: Analysis of Species Diversity and Antifungal Susceptibility.Journal of fungi (Basel, Switzerland) · 2026Article
- Pretreatment of lignocellulosic biomass and biogas production from a microbial consortium recovered from soil litter and termite gut.World journal of microbiology & biotechnology · 2025Article
- The Domestic Isolation of Terbinafine- and Itraconazole-Resistant Trichophyton indotineae in Chinese Mainland.Mycopathologia · 2023Article
- The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment.PLoS pathogens · 2022Article
- Assessment of the Antibacterial Efficacy of Halicin against Pathogenic Bacteria.Antibiotics (Basel, Switzerland) · 2021Article
- The Sensitivity Modifying Activity of Nerolidol and α-Bisabolol AgainstIndian journal of microbiology · 2020Article
- Comparative evaluation of E-test and CLSI methods for Itraconazole, Fluconazole and Ketoconazole susceptibilities of Microsporum canis strains.Mycopathologia · 2020Article
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis.Mycopathologia · 2020Article
- Potential of Gallium as an Antifungal Agent.Frontiers in cellular and infection microbiology · 2019Article
- Butenafine and analogues: An expeditious synthesis and cytotoxicity and antifungal activities.Journal of advanced research · 2018Article
- Therapy and Antifungal Susceptibility Profile ofJournal of fungi (Basel, Switzerland) · 2018Review
- Antidermatophytic Activity of the Fruticose Lichen Usnea orientalis.Medicines (Basel, Switzerland) · 2016Article
- Molecular Characterization and In Vitro Antifungal Susceptibility of 316 Clinical Isolates of Dermatophytes in Iran.Mycopathologia · 2016Article
- Detection of dermatophytes in healthy companion dogs and cats in eastern India.Iranian journal of veterinary research · 2016Article
- 2-(benzylideneamino)phenol: a promising hydroxyaldimine with potent activity against dermatophytoses.Mycopathologia · 2015Article
- Article
- Antifungal and cytotoxicity activities of the fresh xylem sap of Hymenaea courbaril L. and its major constituent fisetin.BMC complementary and alternative medicine · 2014Article
- Dynamic interaction between fluconazole and amphotericin B against Cryptococcus gattii.Antimicrobial agents and chemotherapy · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A total of 92 clinical isolates of dermatophytes (52 of Trichophyton rubrum and 40 of Trichophyton mentagrophytes) were selected for testing with six antifungal drugs (terbinafine, griseofulvin, clotrimazole, miconazole, isoconazole, and fluconazole) and two pairs of drug combinations (ketoconazole-cyclopiroxolamine and itraconazole-cyclopiroxolamine). Two methods of inoculum preparation for susceptibility testing were evaluated that used (i) inocula consisting only of microconidia of dermatophytes filtered in Whatman filter model 40 and (ii) unfiltered inocula consisting of hyphae and microconidia. We followed the recommendations of approved document M38-A of CLSI (formerly NCCLS) with some adaptations, including an incubation period of 7 days and an incubation temperature of 28 degrees C. Reference strains of Candida parapsilosis, Candida krusei, Trichophyton rubrum, and Trichophyton mentagrophytes were included as quality-control strains. MICs were consistently higher (usually 1 to 2 dilutions for drugs tested individually) when nonfiltered inocula were tested (P < 0.01) except for terbinafine. Larger MICs were seen when testing drugs with nonfiltered inocula. The curves of drug interaction were used to analyze the reproducibility of the test, and it was shown that high levels of reproducibility were achieved using the methodology that included the filtration step. The standardization of methodologies is the first step to yield reliability of susceptibility testing and to proceed with clinical laboratory studies to correlate MICs with clinical outcomes.
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