Evidence map›Paper›PMID 16389478›Full record

ArticleMycopathologia2006

Non-glucan attached proteins of Candida albicans biofilm formed on various surfaces.

Govindsamy Vediyappan, W Lajean Chaffin

Open access · greenAbstract read
In one paragraph

Article in Mycopathologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Govindsamy VediyappanDepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA.
W Lajean Chaffin
Texas Tech University · USTexas Tech University Health Sciences Center · US

Funding

Candida albicans oral biofilmR01DE014029 · NIDCR · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI CHAFFIN, WELDA LAJEAN · 2001 to 2004
$1.3M
NIDCR NIH HHS 1R01 DE14029NIDCR NIH HHS R01 DE014029
6 · The paper itself

Abstract

Non-glucan attached proteins of the cell surface and extracellular matrix of Candida albicans biofilms formed on two catheter surfaces and denture acrylic were examined. The SDS-PAGE protein profiles of these proteins compared with that obtained from planktonic yeast cells and germ tubes were generally similar. This observation suggested that this class of biofilm surface proteins is not composed of a unique set of extracellular proteins or that one or a few proteins dominate the non-glucan attached proteins of biofilm. However, differences were observed in the proteins obtained from biofilm formed on one catheter surface and two proteins, Grp2p and ORF19.822p, identified by mass spectrometry following two-dimensional separation. These proteins have previously been associated with drug resistance and their presence or abundance appeared to be influenced by the surface on which the biofilm was formed.

Indexed as

BiofilmsBlotting, WesternCandida albicansCatheterizationDenturesDrug ResistanceElectrophoresis, Gel, Two-DimensionalFungal ProteinsHumansMicroscopy, Electron, ScanningProsthesis-Related InfectionsFungal Proteins

Identifiers

PMID16389478
PMCPMC4957702
OpenAlexW1994083234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.