ArticleGenetics2006
Organization of the sex-ratio meiotic drive region in Drosophila simulans.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Testis- and ovary-expressed polo-like kinase transcripts and gene duplications affect male fertility when expressed in the Drosophila melanogaster germline.G3 (Bethesda, Md.) · 2025Article
- Impacts of Sex Ratio Meiotic Drive on Genome Structure and Function in a Stalk-Eyed Fly.Genome biology and evolution · 2023Article
- Evolution of genome structure in theGenome research · 2021Article
- Meiotic drive mechanisms: lessons fromProceedings. Biological sciences · 2019Article
- Article
- Recurrent Amplification of the Heterochromatin Protein 1 (HP1) Gene Family across Diptera.Molecular biology and evolution · 2018Article
- Contrasting patterns of X-chromosome divergence underlie multiple sex-ratio polymorphisms in stalk-eyed flies.Journal of evolutionary biology · 2017Article
- Rapid evolution of a Y-chromosome heterochromatin protein underlies sex chromosome meiotic drive.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Heterochromatin and genetic conflict.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Spodoptera frugiperda (Lepidoptera: Noctuidae) host-plant variants: two host strains or two distinct species?Genetica · 2015Article
- Sex chromosome drive.Cold Spring Harbor perspectives in biology · 2014Review
- An X-linked sex ratio distorter in Drosophila simulans that kills or incapacitates both noncarrier sperm and sons.G3 (Bethesda, Md.) · 2014Article
- Surprising differences in the variability of Y chromosomes in African and cosmopolitan populations of Drosophila melanogaster.Genetics · 2013Article
- Sequence Analysis of the Segmental Duplication Responsible for Paris Sex-Ratio Drive in Drosophila simulans.G3 (Bethesda, Md.) · 2011Article
- Article
- A single gene causes both male sterility and segregation distortion in Drosophila hybrids.Science (New York, N.Y.) · 2009Article
- Hitchhiking both ways: effect of two interfering selective sweeps on linked neutral variation.Genetics · 2008Article
- A sex-ratio meiotic drive system in Drosophila simulans. I: an autosomal suppressor.PLoS biology · 2007Article
- Out with the old, in with the new: Meiotic driving of sex chromosome evolution.Seminars in cell & developmental biologyReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex-ratio meiotic drive is the preferential transmission of the X chromosome by XY males, which occurs in several Drosophila species and results in female-biased progeny. Although the trait has long been known to exist, its molecular basis remains completely unknown. Here we report a fine-mapping experiment designed to characterize the major drive locus on a sex-ratio X chromosome of Drosophila simulans originating from the Seychelles (XSR6). This primary locus was found to contain two interacting elements at least, both of which are required for drive expression. One of them was genetically tracked to a tandem duplication containing six annotated genes (Trf2, CG32712, CG12125, CG1440, CG12123, org-1), and the other to a candidate region located approximately 110 kb away and spanning seven annotated genes. RT-PCR showed that all but two of these genes were expressed in the testis of both sex-ratio and standard males. In situ hybridization to polytene chromosomes revealed a complete association of the duplication with the sex-ratio trait in random samples of X chromosomes from Madagascar and Reunion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.