ArticleHeart (British Cardiac Society)2006
Declining case fatality rates for acute myocardial infarction in South Asian and white patients in the past 15 years.
Article in Heart (British Cardiac Society), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- The global prevalence of myocardial infarction: a systematic review and meta-analysis.BMC cardiovascular disorders · 2023Pooled it
- South Asians and coronary disease: is there discordance between effects on incidence and prognosis?Heart (British Cardiac Society) · 2013Pooled it
- Plasma expression of lncRNA Wisper in patients with heart failure and patients with myocardial infarction.Future cardiology · 2025Article
- Vitamin C as Scavenger of Reactive Oxygen Species during Healing after Myocardial Infarction.International journal of molecular sciences · 2024Review
- Article
- Molecular basis of cardioprotective effect of antioxidant vitamins in myocardial infarction.BioMed research international · 2013Review
- Article
- Outcomes in a diabetic population of South Asians and whites following hospitalization for acute myocardial infarction: a retrospective cohort study.Cardiovascular diabetology · 2010Article
- Long-term trend in the incidence of acute myocardial infarction in Korea: 1997-2007.Korean circulation journal · 2009Article
- Population impact of regulatory activity restricting prescribing of COX-2 inhibitors: ecological study.British journal of clinical pharmacology · 2009Article
- Trends for coronary heart disease and stroke mortality among migrants in England and Wales, 1979-2003: slow declines notable for some groups.Heart (British Cardiac Society) · 2008Article
- Country of birth and survival after a first myocardial infarction in Stockholm, Sweden.European journal of epidemiology · 2008Article
- Patients with cardiac chest pain should call emergency services.BMJ (Clinical research ed.) · 2007Review
- Record linked retrospective cohort study of 4.6 million people exploring ethnic variations in disease: myocardial infarction in South Asians.BMC public health · 2007Article
- Ethnicity and cardiovascular disease prevention in the United Kingdom: a practical approach to management.Journal of human hypertension · 2007Review
- Risk assessment after acute coronary syndrome.BMJ (Clinical research ed.) · 2006Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine whether case fatality rates in South Asian (Bangladeshi, Indian and Pakistani) patients with acute myocardial infarction have shown similar declines to those reported for white patients during the past 15 years.
designCross-sectional, observational study.
settingCoronary care unit in east London. PATIENTS: 2640 patients-29% South Asian-admitted with acute myocardial infarction between January 1988 and December 2002.
main outcome measuresDifferences over time in rates of in-hospital death, ventricular fibrillation and left ventricular failure.
resultsThe proportion of South Asians increased from 22% in 1988-92 to 37% in 1998-2002. Indices of infarct severity were similar in South Asian and white patients, with declining frequencies of ST elevation infarction (88.2% to 77.5%, p < 0.0001), Q wave development (78.1% to 56.9%, p < 0.0001) and mean (interquartile range) peak serum creatine kinase concentrations (1250 (567-2078) to 1007 (538-1758) IU/l, p < 0.0001) between 1988-92 and 1998-2002. Rates of in-hospital death (13.0% to 9.4%, p < 0.01), ventricular fibrillation (9.2% to 6.0%, p < 0.001) and left ventricular failure (33.2% to 26.5%, p < 0.0001) all declined; these changes did not interact significantly with ethnicity. Odds ratios for the effect of time on risk of death increased from 0.81 (95% CI 0.70 to 0.93) to 1.02 (95% CI 0.87 to 1.21) after adjustment for ethnicity and indices of infarct severity (ST elevation, peak creatine kinase, Q wave development and treatment with a thrombolytic).
conclusionsIn the past 15 years, death from acute myocardial infarction among South Asians has declined at a rate similar to that seen in white patients. This is largely caused by reductions in indices of infarct severity.
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