ArticleBiophysical journal2006
Sphingomyelin structure influences the lateral diffusion and raft formation in lipid bilayers.
Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Shared and distinct lipid profiles in amygdala from sporadic and GBA-associated Parkinson's diseases.NPJ Parkinson's disease · 2026Article
- Dimeric Polyphenol Effect on Liquid-Ordered and Liquid-Disordered Membranes: Combined Insights from Molecular Dynamics Simulation and Langmuir Balance Measurements.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Engineered Lipidic Nanomaterials Inspired by Sphingomyelin Metabolism for Cancer Therapy.Molecules (Basel, Switzerland) · 2023Review
- Machine-learning-powered extraction of molecular diffusivity from single-molecule images for super-resolution mapping.Communications biology · 2023Article
- Article
- The therapeutic potential of sphingolipids for cardiovascular diseases.Frontiers in cardiovascular medicine · 2023Review
- Structure and Interdigitation of Chain-Asymmetric Phosphatidylcholines and Milk Sphingomyelin in the Fluid Phase.Symmetry · 2021Article
- Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damageAging · 2020Article
- Sphingomyelins Prevent Propagation of Lipid Peroxidation-LC-MS/MS Evaluation of Inhibition Mechanisms.Molecules (Basel, Switzerland) · 2020Article
- Sphingomyelin Synthase 2 Inhibition Ameliorates Cerebral Ischemic Reperfusion Injury Through Reducing the Recruitment of Toll-Like Receptor 4 to Lipid Rafts.Journal of the American Heart Association · 2019Article
- The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol.Scientific reports · 2019Article
- Lipid nanodomains change ion channel function.Nanoscale · 2017Article
- Phase Composition Control in Microsphere-Supported Biomembrane Systems.Langmuir : the ACS journal of surfaces and colloids · 2017Article
- Ordered raft domains induced by outer leaflet sphingomyelin in cholesterol-rich asymmetric vesicles.Biophysical journal · 2015Article
- N-nervonoylsphingomyelin (C24:1) prevents lateral heterogeneity in cholesterol-containing membranes.Biophysical journal · 2014Article
- Crystallization around solid-like nanosized docks can explain the specificity, diversity, and stability of membrane microdomains.Frontiers in plant science · 2014Article
- Nitric oxide-sphingolipid interplays in plant signalling: a new enigma from the Sphinx?Frontiers in plant science · 2013Review
- Acyl chain length and saturation modulate interleaflet coupling in asymmetric bilayers: effects on dynamics and structural order.Biophysical journal · 2012Article
- Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains.Biophysical journal · 2012Article
- pH Effect of the sphingomyelin membrane interfacial tension.The Journal of membrane biology · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liquid-disordered/liquid-ordered two-phase coexistence regions in hydrated bilayers have been investigated for sphingomyelins (SMs) of three different origins: egg, brain, and milk with the pulsed-field gradient NMR technique for lateral diffusion measurement. It is found that the three SMs have the same diffusional behavior in bilayers of SM alone, but in the multicomponent systems of dioleoylphosphatidylcholine/SM/cholesterol, the ability to form domains differs for the three SMs. The two-phase area is more extended for egg SM than for brain SM, and no two-phase coexistence is found for milk SM. The differences in behavior are correlated with the homogeneity of the SM hydrocarbon chain compositions, in which egg SM has the most homogeneous and milk SM has the most heterogeneous composition. The results indicate that a crucial element in the domain-forming process is the formation of highly packed bilayers of SM and cholesterol rather than specific interactions between SM and cholesterol.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.