ArticlePlant physiology2006
A universal role for inositol 1,4,5-trisphosphate-mediated signaling in plant gravitropism.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 152 citations in OpenAlex.
- Primary nitrate responses mediated by calcium signalling and diverse protein phosphorylation.Journal of experimental botany · 2020Pooled it
- A molecular perspective on the role of FERONIA in root growth, nutrient uptake, stress sensing and microbiome assembly.Journal of advanced research · 2025Review
- Epiallelic Variation of TILLER ANGLE CONTROL 5 (TAC5) Regulates Tiller Angle by Modulating Gravitropism in Rice.Rice (New York, N.Y.) · 2025Article
- KRN5b regulates maize kernel row number through mediating phosphoinositol signalling.Plant biotechnology journal · 2024Article
- Characterization ofPlants (Basel, Switzerland) · 2024Article
- ITPK1 Regulates Jasmonate-Controlled Root Development inBiomolecules · 2023Article
- Insight into the role of clathrin-mediated endocytosis inhibitors in SARS-CoV-2 infection.Reviews in medical virology · 2023Review
- Transcriptome and hormone metabolome reveal the mechanism of stem bending in water lily (Frontiers in plant science · 2023Article
- Plant Gravitropism: From Mechanistic Insights into Plant Function on Earth to Plants Colonizing Other Worlds.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Regulation of plant biotic interactions and abiotic stress responses by inositol polyphosphates.Frontiers in plant science · 2022Review
- Subcellular trafficking and post-translational modification regulate PIN polarity in plants.Frontiers in plant science · 2022Review
- Characterization of a Novel Creeping Tartary Buckwheat (Frontiers in plant science · 2022Article
- Energy-Saving LED Light Affects the Efficiency of the Photosynthetic Apparatus and Carbohydrate Content inBiology · 2021Article
- The AtCRK5 Protein Kinase Is Required to Maintain the ROS NO Balance Affecting the PIN2-Mediated Root Gravitropic Response in Arabidopsis.International journal of molecular sciences · 2021Article
- Link between Lipid Second Messengers and Osmotic Stress in Plants.International journal of molecular sciences · 2021Review
- Abscisic Acid Regulates the Root Growth Trajectory by Reducing Auxin TransporterFrontiers in plant science · 2021Article
- Gravity Signaling in Flowering Plant Roots.Plants (Basel, Switzerland) · 2020Review
- A putative tomato inositol polyphosphate 5-phosphatase, Le5PT1, is involved in plant growth and abiotic stress responses.3 Biotech · 2020Article
- Root Tropisms: Investigations on Earth and in Space to Unravel Plant Growth Direction.Frontiers in plant science · 2019Review
- The Tonoplastic Inositol Transporter INT1 FromFrontiers in plant science · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inositol 1,4,5-trisphosphate (InsP3) has been implicated in the early signaling events of plants linking gravity sensing to the initiation of the gravitropic response. However, at present, the contribution of the phosphoinositide signaling pathway in plant gravitropism is not well understood. To delineate the role of InsP3 in plant gravitropism, we generated Arabidopsis (Arabidopsis thaliana) plants constitutively expressing the human type I inositol polyphosphate 5-phosphatase (InsP 5-ptase), an enzyme that specifically hydrolyzes InsP3. The transgenic plants show no significant differences in growth and life cycle compared to wild-type plants, although basal InsP3 levels are reduced by greater than 90% compared to wild-type plants. With gravistimulation, InsP3 levels in inflorescence stems of transgenic plants show no detectable change, whereas in wild-type plant inflorescences, InsP3 levels increase approximately 3-fold within the first 5 to 15 min of gravistimulation, preceding visible bending. Furthermore, gravitropic bending of the roots, hypocotyls, and inflorescence stems of the InsP 5-ptase transgenic plants is reduced by approximately 30% compared with the wild type. Additionally, the cold memory response of the transgenic plants is attenuated, indicating that InsP3 contributes to gravisignaling in the cold. The transgenic roots were shown to have altered calcium sensitivity in controlling gravitropic response, a reduction in basipetal indole-3-acetic acid transport, and a delay in the asymmetric auxin-induced beta-glucuronidase expression with gravistimulation as compared to the controls. The compromised gravitropic response in all the major axes of growth in the transgenic Arabidopsis plants reveals a universal role for InsP3 in the gravity signal transduction cascade of plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.