ArticleEuropean archives of psychiatry and clinical neuroscience2005
Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters.
Article in European archives of psychiatry and clinical neuroscience, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Integrating Forensic Autopsies with Proteomic Profiling for Suicide Risk Assessment: A Comprehensive Review of Literature.Current neuropharmacology · 2025Pooled it
- Altered tRNA expression profile associated with codon-specific proteomic changes in the suicide brain.Molecular psychiatry · 2025Article
- Alzheimer's Disease and Suicide: An Integrative Literature Review.Current Alzheimer research · 2024Review
- 'Omics' of suicidal behaviour: A path to personalised psychiatry.World journal of psychiatry · 2021Review
- Downregulation of apolipoprotein A-IV in plasma & impaired reverse cholesterol transport in individuals with recent acts of deliberate self-harm.The Indian journal of medical research · 2019Article
- Back to the Future - Part 2. Post-mortem assessment and evolutionary role of the bio-medicolegal sciences.International journal of legal medicine · 2017Review
- The neurobiology of suicide - A Review of post-mortem studies.Journal of molecular psychiatry · 2013Review
- Cerebrospinal fluid biomarkers for major depression confirm relevance of associated pathophysiology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- Postmortem proteomic analysis in human amygdala of drug addicts: possible impact of tubulin on drug-abusing behavior.European archives of psychiatry and clinical neuroscience · 2011Article
- Pharmacogenomics of suicidal events.Pharmacogenomics · 2010Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This is the first report on proteomic analysis of the cerebrospinal fluid (CSF) in unmedicated suicide attempters and non-attempters with major depressive disorder. Two-dimensional (2D) gel electrophoresis revealed that suicide attempters differed from non-attempters in one protein with an approximate molecular weight of 33 kD and an isoelectric point of 5.2. Proteomic analysis of the CSF is a promising non hypothesis-driven screening method for the detection of new candidate genes in neurobiological suicide research.
Indexed as
Identifiers
16382377What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.