ArticleDevelopment genes and evolution2006
Molecular control of serial module formation along the apical-basal axis in the sponge Lubomirskia baicalensis: silicateins, mannose-binding lectin and mago nashi.
Article in Development genes and evolution, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 67 citations in OpenAlex.
- Directed Evolution of Silicatein Reveals Biomineralization Synergism between Protein Sequences.ACS omega · 2025Article
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- A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022Article
- The EJC component Magoh in non-vertebrate chordates.Development genes and evolution · 2020Article
- Lectin-Like Bacteriocins.Frontiers in microbiology · 2018Review
- Review
- A Proposal for the Evolution of Cathepsin and Silicatein in Sponges.Journal of molecular evolution · 2015Article
- RNA interference can be used to disrupt gene function in tardigrades.Development genes and evolution · 2013Article
- Structural determinants for activity and specificity of the bacterial toxin LlpA.PLoS pathogens · 2013Article
- Mannan-binding lectin of the sea urchin Strongylocentrotus nudus.Marine biotechnology (New York, N.Y.) · 2013Article
- Involvement of Wnt signaling pathways in the metamorphosis of the bryozoan Bugula neritina.PloS one · 2012Article
- Occurrence of a silicatein gene in glass sponges (Hexactinellida: Porifera).Marine biotechnology (New York, N.Y.) · 2011Article
- Enzymatic production of biosilica glass using enzymes from sponges: basic aspects and application in nanobiotechnology (material sciences and medicine).Die Naturwissenschaften · 2007Review
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The freshwater sponge Lubomirskia baicalensis (from Lake Baikal) is characterized by a body plan composed of serial modules which are arranged along an apical-basal axis. In shallow water, the sponge occurs only encrusting, while in deeper environment (>3 m), this species forms branches and grows in an arborescent manner. Each module is stabilized by bundles of spined oxeas (amphioxeae spicules). The spicules are surrounded by an organic matrix. cDNAs for structural proteins (silicatein and mannose-binding lectin (MBL)) as well as for one regulatory protein (mago nashi) were isolated from L. baicalensis. Surprisingly the silicatein alpha molecule exists in several, at least four, isoforms (a1 to a4). Expression studies revealed that the steady-state levels of transcripts for the silicateins, the mannose-binding lectin, and mago nashi are highest at the top of the branches, while only very low levels are found in cells at the base. Based on in situ hybridization studies, evidence is presented that the spicule formation (1) starts and is completed inside of the bundles, and (2) occurs together with the mannose-binding lectin from the surfaces of the bundles. The data suggest that the modules are sequentially formed. It is speculated that the expression of the silicateins and the mannose-binding lectin might be (partially) controlled by mago nashi.
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