ArticleParasitology research2006
Detection of putative secreted proteins in the plant-parasitic nematode Heterodera schachtii.
Article in Parasitology research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Life-stage specific transcriptomes of a migratory endoparasitic plant nematode, Radopholus similis elucidate a different parasitic and life strategy of plant parasitic nematodes.Scientific reports · 2019Article
- Molecular Characterization of A Novel Effector Expansin-like Protein from Heterodera avenae that Induces Cell Death in Nicotiana benthamiana.Scientific reports · 2016Article
- A cyst nematode effector binds to diverse plant proteins, increases nematode susceptibility and affects root morphology.Molecular plant pathology · 2016Article
- Identification and functional analysis of secreted effectors from phytoparasitic nematodes.BMC microbiology · 2016Review
- Analysis of the Transcriptome of the Infective Stage of the Beet Cyst Nematode, H. schachtii.PloS one · 2016Article
- Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus.The Biochemical journal · 2015Article
- De novo transcriptome sequencing and analysis of the cereal cyst nematode, Heterodera avenae.PloS one · 2014Article
- Article
- Exploring the host parasitism of the migratory plant-parasitic nematode Ditylenchus destuctor by expressed sequence tags analysis.PloS one · 2013Article
- Multiple lateral gene transfers and duplications have promoted plant parasitism ability in nematodes.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Transcripts analysis of the entomopathogenic nematode Steinernema carpocapsae induced in vitro with insect haemolymph.Molecular and biochemical parasitology · 2010Article
- Identification and functional characterization of effectors in expressed sequence tags from various life cycle stages of the potato cyst nematode Globodera pallida.Molecular plant pathology · 2009Article
- Expressed sequence tags of the peanut pod nematode Ditylenchus africanus: the first transcriptome analysis of an Anguinid nematode.Molecular and biochemical parasitology · 2009Article
- The transcriptome of syncytia induced by the cyst nematode Heterodera schachtii in Arabidopsis roots.The Plant journal : for cell and molecular biology · 2009Article
- Article
- Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs).PLoS neglected tropical diseases · 2008Article
- On the extent and origins of genic novelty in the phylum Nematoda.PLoS neglected tropical diseases · 2008Article
- Mining the secretome of the root-knot nematode Meloidogyne chitwoodi for candidate parasitism genes.Molecular plant pathology · 2008Article
- Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines.Genome biology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The beet cyst nematode Heterodera schachtii is an important pathogen worldwide, but its molecular characterization has been limited to studying individual genes of interest. We undertook a high-throughput genomic approach and drastically increased the number of available sequences for this parasite. A total of 2,662 expressed sequence tags were grouped into 1,212 clusters representing a nonredundant catalog of H. schachtii genes. Implementing a bioinformatic workflow, we identified 50 sequences coding for candidate secreted proteins. All of these contain a putative signal peptide required for entry into the secretory pathway and lack any transmembrane domain. Included are previously postulated cell-wall-degrading enzymes and other parasitism-related genes. Moreover, we provide the first report of an arabinogalactan endo-1,4-beta-galactosidase enzyme (EC 3.2.1.89) in animals. As sequence data increase at a rapid rate, developing high-throughput genomic screening is a necessity. The in silico approach described here is an effective way to identify putative secreted proteins and prioritize candidates for further studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.