Evidence map›Paper›PMID 16380834›Full record

ArticleNeuroscience and behavioral physiology2006

Protein synthesis-dependent reactivation of a contextual conditioned reflex in the common snail.

T Kh Gainutdinova, R R Tagirova, A I Ismailova, L N Muranova, Kh L Gainutdinov, P M Balaban

Abstract read
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In one paragraph

Article in Neuroscience and behavioral physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

T Kh GainutdinovaKazan' Physicotechnical Institute, Kazan' Scientific Center, Russian Academy of Sciences, Moscow.
R R Tagirova
A I Ismailova
L N Muranova
Kh L Gainutdinov
P M Balaban
Kazan Scientific Center · RURussian Academy of Sciences · RUInstitute of Higher Nervous Activity and Neurophysiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here a study of the effects of blockade of protein synthesis with anisomycin during reactivation of a contextual conditioned reflex in the common snail. The amplitudes of the defensive reactions of snails to standard tactile stimulation before training were identical in two conditions: 1) testing of responses of snails fixed by the shell to a plastic ball floating in water and 2) on the surface of the terrarium glass. After applying electric shocks to the snails' skin for 5 days, a significant difference in responses reflecting the formation of a contextual conditioned reflex was seen in only one of the contexts. Placing trained snails in the same context (reminding) two days after training with simultaneous injection of anisomycin led to significant weakening of training, while control injections of physiological saline produced no such changes. These data suggest that the mechanisms of memory consolidation after training and reminding are not identical.

Indexed as

AnimalsAnisomycinAvoidance LearningConditioning, ClassicalHelix, SnailsMental RecallProtein BiosynthesisProtein Synthesis InhibitorsAnisomycinProtein Synthesis Inhibitors

Identifiers

PMID16380834
OpenAlexW2092432330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.