Evidence map›Paper›PMID 16378968›Full record

ArticleJournal of virology2006

The transcription profile of Aleutian mink disease virus in CRFK cells is generated by alternative processing of pre-mRNAs produced from a single promoter.

Jianming Qiu, Fang Cheng, Lisa R Burger, David Pintel

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 76 citations in OpenAlex.

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  8. AMDOPARVOVIRUS INFECTIONS ARE PREVALENT, PERSISTENT, AND GENETICALLY DIVERSE IN ZOO-HOUSED RED PANDAS (Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jianming QiuDepartment of Molecular Microbiology and Immunology, University of Missouri-Columbia, School of Medicine, Life Sciences Center, 1201 E. Rollins Rd., Columbia, MO 65211-7310, USA. qiuj@missouri.edu
Fang Cheng
Lisa R Burger
David Pintel
University of Missouri · US

Funding

Adeno-associated Virus RNA Splicing and PolyadenylationR01AI056310 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 2004 to 2013
$3.4M
MOLECULAR &GENETIC ANALYSIS OF MVM GENE EXPRESSIONR01AI021302 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 1985 to 2008
$2.4M
NIAID NIH HHS R01 AI021302NIAID NIH HHS R01 AI056310NIAID NIH HHS R01 AI21302NIAID NIH HHS R01 AI56310
6 · The paper itself

Abstract

A reevaluation of the transcription profile of Aleutian mink disease parvovirus (AMDV)-infected CRFK cells at either 32 degrees C or 37 degrees C has determined that strain AMDV-G encodes six species of mRNAs produced by alternative splicing and alternative polyadenylation of a pre-mRNA generated by a single promoter at the left end of the genome. Three different splicing patterns are used, and each type is found polyadenylated at either the 3' end of the genome (the distal site) or at a site in the center of the genome (the proximal site). All spliced species accumulate similarly over the course of infection, with the R2 RNA predominant throughout. The R2 RNA, which contains and can express the NS2 coding region, encodes the viral capsid proteins VP1 and VP2.

Indexed as

Genome, ViralAleutian Mink Disease VirusAlternative SplicingAnimalsCapsid ProteinsCell LinePolyadenylationPromoter Regions, GeneticRNA, MessengerRNA, ViralTemperatureTranscription, GeneticCapsid ProteinsRNA, MessengerRNA, ViralVP2 protein, Aleutian mink disease virus

Identifiers

PMID16378968
PMCPMC1346859
OpenAlexW2037143659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.