ArticlePlant physiology2006
Transcript analysis of early nodulation events in Medicago truncatula.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
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Who cites it
99 citing papers in PubMed.
- Systemic proteome remodeling in soybean during early nodulation: distinct responses in roots and leaves.Frontiers in plant science · 2026Article
- The short chitooligosaccharide CO4 inhibits chitin-triggered immunity in grapevine and promotes the infection by Botrytis cinerea but not Plasmopara viticola.Journal of experimental botany · 2025Article
- Alleviation of water stress in soybean symbiosis by salicylic acid and methyl jasmonate-activated Bradyrhizobium.BMC plant biology · 2025Article
- Ca2+ signatures in symbiosis: another level of dynamism for this key messenger.Journal of experimental botany · 2024Article
- Single-nucleus transcriptomes reveal spatiotemporal symbiotic perception and early response in Medicago.Nature plants · 2023Article
- A Germin-Like Protein GLP1 of Legumes Mediates Symbiotic Nodulation by Interacting with an Outer Membrane Protein of Rhizobia.Microbiology spectrum · 2023Article
- Legumes Regulate Symbiosis with Rhizobia via Their Innate Immune System.International journal of molecular sciences · 2023Review
- Right time, right place: The dynamic role of hormones in rhizobial infection and nodulation of legumes.Plant communications · 2022Review
- Innovation and appropriation in mycorrhizal and rhizobial Symbioses.The Plant cell · 2022Article
- Transcriptomic analysis of Mesoamerican and Andean Phaseolus vulgaris accessions revealed mRNAs and lncRNAs associated with strain selectivity during symbiosis.Scientific reports · 2022Article
- Bridging the Gap: Type III Secretion Systems in Plant-Beneficial Bacteria.Microorganisms · 2022Article
- The effects of ERN1 on gene expression during early rhizobial infection inFrontiers in plant science · 2022Article
- Application of CRISPR-Cas9 in plant-plant growth-promoting rhizobacteria interactions for next Green Revolution.3 Biotech · 2021Review
- Legume-rhizobium dance: an agricultural tool that could be improved?Microbial biotechnology · 2021Review
- Involvement of Arachis hypogaea Jasmonate ZIM domain/TIFY proteins in root nodule symbiosis.Journal of plant research · 2021Article
- The Rhizobium-Legume Symbiosis: Co-opting Successful Stress Management.Frontiers in plant science · 2021Review
- Fulvic acid increases forage legume growth inducing preferential up-regulation of nodulation and signalling-related genes.Journal of experimental botany · 2020Article
- Responses of mature symbiotic nodules to the whole-plant systemic nitrogen signaling.Journal of experimental botany · 2020Article
- Article
- Suppression of NB-LRR genes by miRNAs promotes nitrogen-fixing nodule development in Medicago truncatula.Plant, cell & environment · 2020Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Within the first 72 h of the interaction between rhizobia and their host plants, nodule primordium induction and infection occur. We predicted that transcription profiling of early stages of the symbiosis between Medicago truncatula roots and Sinorhizobium meliloti would identify regulated plant genes that likely condition key events in nodule initiation. Therefore, using a microarray with about 6,000 cDNAs, we compared transcripts from inoculated and uninoculated roots corresponding to defined stages between 1 and 72 h post inoculation (hpi). Hundreds of genes of both known and unknown function were significantly regulated at these time points. Four stages of the interaction were recognized based on gene expression profiles, and potential marker genes for these stages were identified. Some genes that were regulated differentially during stages I (1 hpi) and II (6-12 hpi) of the interaction belong to families encoding proteins involved in calcium transport and binding, reactive oxygen metabolism, and cytoskeleton and cell wall functions. Genes involved in cell proliferation were found to be up-regulated during stages III (24-48 hpi) and IV (72 hpi). Many genes that are homologs of defense response genes were up-regulated during stage I but down-regulated later, likely facilitating infection thread progression into the root cortex. Additionally, genes putatively involved in signal transduction and transcriptional regulation were found to be differentially regulated in the inoculated roots at each time point. The findings shed light on the complexity of coordinated gene regulation and will be useful for continued dissection of the early steps in symbiosis.
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