Evidence map›Paper›PMID 16374655›Full record

ArticleJournal of fluorescence2006

Microwave-accelerated metal-enhanced fluorescence (MAMEF): application to ultra fast and sensitive clinical assays.

Kadir Aslan, Chris D Geddes

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kadir AslanInstitute of Fluorescence, Laboratory for Advanced Medical Plasmonics, Medical Biotechnology Center, University of Maryland Biotechnology Institute, 725 West Lombard St., Baltimore, Maryland, USA.
Chris D Geddes
University of Maryland, Baltimore · US

Funding

Metal-Enhanced Fluorescence RNA SensingR21GM070929 · NIGMS · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI GEDDES, CHRISTOPHER DARREN · 2004 to 2005
$238k
NCRR NIH HHS RR008119NIGMS NIH HHS GM070929
6 · The paper itself

Abstract

In this rapid communication we describe an exciting platform technology that promises to fundamentally address two underlying constraints of modern assays and immunoassays, namely sensitivity and rapidity. By combining the use of Metal-enhanced Fluorescence (MEF) with low power microwave heating (Mw), we can significantly increase the sensitivity of surface assays as well as >95% kinetically complete the assay within a few seconds. This technology is subsequently likely to find significant importance in certain clinical assays, such as in the clinical assessment of myoglobin, where both the assay rapidity and sensitivity are paramount for the assessment and treatment of acute myocardial infarction.

Indexed as

FluorescenceMicrowavesHumansImmunoassayMicroscopy, Atomic ForceModels, BiologicalMyoglobinNanostructuresSensitivity and SpecificitySilverSpectrometry, FluorescenceSurface PropertiesTime FactorsMyoglobinSilver

Identifiers

PMID16374655
OpenAlexW2158664284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.