ReviewHandbook of experimental pharmacology2006
Cardiac repair by embryonic stem-derived cells.
Review in Handbook of experimental pharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Stem Cell Therapy: A Compassionate Use Program in Perianal Fistula.Stem cells international · 2019Article
- Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish.Nature communications · 2016Article
- Treatment of Crohn's-Related Rectovaginal Fistula With Allogeneic Expanded-Adipose Derived Stem Cells: A Phase I-IIa Clinical Trial.Stem cells translational medicine · 2016Article
- Stem cell procedures in arthroscopic surgery.European journal of medical research · 2016Review
- Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling.Stem cell research & therapy · 2014Article
- Application of stem cells in orthopedics.Stem cells international · 2012Article
- Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues.Journal of materials science. Materials in medicine · 2011Article
- Diabetic cardiomyopathy: signaling defects and therapeutic approaches.Expert review of cardiovascular therapy · 2010Review
- Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis.Journal of molecular and cellular cardiology · 2008Review
- Stem cell differentiation: cardiac repair.Cells, tissues, organs · 2008Review
- Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts.Journal of molecular and cellular cardiology · 2007Article
- Cell-based approaches for cardiac repair.Annals of the New York Academy of Sciences · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cell transplantation approaches offer the potential to promote regenerative growth of diseased hearts. It is well established that donor cardiomyocytes stably engraft into recipient hearts when injected directly into the myocardial wall. Moreover, the transplanted donor cardiomyocytes participate in a functional syncytium with the host myocardium. Thus, transplantation of donor cardiomyocytes resulted in at least partial restoration of lost muscle mass. It is also well established that embryonic stem (ES) cells differentiate into cells of ecto-, endo-, and mesodermal lineages when cultured under appropriate conditions in vitro. Robust cardiomyogenic differentiation was frequently observed in spontaneously differentiating ES cultures. Cellular, molecular and physiologic analyses indicated that ES-derived cells were bona fide cardiomyocytes, with in vitro characteristics typical for cells obtained from early stages of cardiac development. Thus, ES-derived cardiomyocytes constitute a viable source of donor cells for cell transplantation therapies.
Indexed as
Identifiers
16370325PMC2628758What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.