ArticleInternational journal of legal medicine2006
Sudden death after isobutane sniffing: a report of two forensic cases.
Article in International journal of legal medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Rare but relevant: Hydrocarbons and sudden sniffing syndrome.Addiction (Abingdon, England) · 2025Review
- Is it worth carrying out determination of N-butane in postmortem samples? A case report and a comprehensive review of the literature.International journal of legal medicine · 2016Review
- Ataxia with Parkinsonism and dystonia after intentional inhalation of liquefied petroleum gas.Neuropsychiatric disease and treatment · 2015Article
- Volatile substance misuse: an updated review of toxicity and treatment.Clinical reviews in allergy & immunology · 2014Review
- Inhalant abuse: An exploratory study.Industrial psychiatry journal · 2011Article
- Item response theory analysis of DSM-IV criteria for inhalant-use disorders in adolescents.Journal of studies on alcohol and drugs · 2010Article
- Inhalant withdrawal as a clinically significant feature of inhalant dependence disorder.Medical hypotheses · 2009Article
- Cardiac oxidative stress determination and myocardial morphology after a single ecstasy (MDMA) administration in a rat model.International journal of legal medicine · 2008Article
- Evaluation of postmortem measurement of NT-proBNP as a marker for cardiac function.International journal of legal medicine · 2008Article
- Sudden death due to subarachnoid bleeding from ecchordosis physaliphora.International journal of legal medicine · 2008Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intentional inhalation of a volatile substance ("sniffing") causing euphoria and hallucinations is an under-recognised form of substance abuse in children and adolescents with a high morbidity and mortality. Sudden death can be caused by cardiac arrhythmia, asphyxia or trauma. Two fatal cases of isobutane sniffing of cigarette lighter refill containing isobutane are reported. Toxicological investigations revealed the presence of isobutane in the heart blood and brain tissue of both cases (case 1: heart blood 0.1 microg/g, brain tissue 2.3 microg/g; case 2: heart blood 4.6 microg/g, brain tissue 17.4 microg/g) and the presence of its metabolite 2-methyl-2-propanol in the heart blood of both cases (0.5 and 1.8 microg/g, respectively). The histological investigations of the inner organs showed similar results in both victims. Autopsy findings, results of the histological and immunohistochemical investigations, toxicological findings and analytical procedures are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.