ArticleEuropean journal of applied physiology2006
Effects of pedal frequency on estimated muscle microvascular O2 extraction.
Article in European journal of applied physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Effects of 2 weeks of low-intensity cycle training with different pedaling rates on the work rate at lactate threshold.European journal of applied physiology · 2015Trial
- Muscle microvascular oxygen delivery limitations during the contraction phase of intermittent maximal effort contractions.European journal of applied physiology · 2025Article
- Skeletal muscle oxygenation during cycling at different power output and cadence.Physiological reports · 2019Article
- Vasoconstrictor responsiveness through alterations in relaxation time and metabolic rate during rhythmic handgrip contractions.Physiological reports · 2018Article
- Elevated baseline work rate slows pulmonary oxygen uptake kinetics and decreases critical power during upright cycle exercise.Physiological reports · 2018Article
- Effect of exercise-induced muscle damage on vascular function and skeletal muscle microvascular deoxygenation.Physiological reports · 2016Article
- Oxygenation, local muscle oxygen consumption and joint specific power in cycling: the effect of cadence at a constant external work rate.European journal of applied physiology · 2016Article
- Effect of pedaling cadence on muscle oxygenation during high-intensity cycling until exhaustion: a comparison between untrained subjects and triathletes.European journal of applied physiology · 2015Article
- The effect of resting blood flow occlusion on exercise tolerance and W'.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Article
- Influence of blood flow occlusion on the development of peripheral and central fatigue during small muscle mass handgrip exercise.The Journal of physiology · 2015Article
- The impact of pedal rate on muscle oxygenation, muscle activation and whole-body VO₂ during ramp exercise in healthy subjects.European journal of applied physiology · 2015Article
- Enhanced muscle pump during mild dynamic leg exercise inhibits sympathetic vasomotor outflow.Physiological reports · 2014Article
- Significant molecular and systemic adaptations after repeated sprint training in hypoxia.PloS one · 2013Article
- Noninvasive evaluation of skeletal muscle mitochondrial capacity with near-infrared spectroscopy: correcting for blood volume changes.Journal of applied physiology (Bethesda, Md. : 1985) · 2012Article
- The oxygen delivery response to acute hypoxia during incremental knee extension exercise differs in active and trained males.Dynamic medicine : DM · 2008Article
- The role of muscle pump in the development of cardiovascular drift.European journal of applied physiology · 2008Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increase in muscle contraction frequency could limit muscle blood flow QM compromising the matching of QM and muscle oxygen uptake VO2M. This study examined the effects of pedal cadence on skeletal muscle oxygenation at low, moderate and peak exercise. Nine healthy subjects [24.7+/-6.3 years (SD)] performed incremental cycling exercise at 60 and 100 rpm. Pulmonary VO2(VO2P) was measured breath-by-breath and vastus lateralis oxygenation was determined by near-infrared spectroscopy (NIRS). The deoxyhemoglobin signal ([HHb]) from NIRS was used to estimate microvascular O2 extraction (i.e., [HHb] proportional, variant VO2M/QM). The VO2P and [HHb] for low, moderate and at peak exercise were determined. The VO2P at 60 rpm (low=0.64+/-0.13, moderate=2.03+/-0.38 and peak=3.39+/-0.84 l/min) were lower (P<0.01) than at 100 rpm (1.29+/-0.23, 2.14+/-0.39 and 3.54+/-0.88 l/min, respectively). There was a progressive increase in [HHb] from low to peak exercise. However, there was no significant difference (ANOVA, P=0.94) for the 60 (in microM, low=24.0+/-9.5, moderate=30.5+/-13.8 and peak=36.7+/-16.5) and 100 contractions/min (in microM, low=25.7+/-11.6, moderate=32.1+/-14.0 and peak=35.4+/-16.5). We conclude that vastus lateralis O2 extraction was similar at 60 and 100 cpm, suggesting that the VO2M/QM in the microcirculation was not altered and, presumably, no impairment of QM occurred with the increase in pedal frequency.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.