ArticleEuropean journal of pediatrics2006
Should healthy children be vaccinated against influenza? A consensus report of the Summits of Independent European Vaccination Experts.
Article in European journal of pediatrics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Burden of paediatric influenza in Western Europe: a systematic review.BMC public health · 2012Pooled it
- Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for influenza vaccination in children.BMC infectious diseases · 2010Guideline
- Influenza school-based vaccination: A way to increase equity among children.Human vaccines & immunotherapeutics · 2025Observational
- Article
- Immediate and long-term changes in the epidemiology, infection spectrum, and clinical characteristics of viral and bacterial respiratory infections in Western China after the COVID-19 outbreak: a modeling study.Archives of virology · 2023Article
- Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations.Therapeutic advances in vaccines and immunotherapy · 2019Review
- Article
- Article
- Clinical and socioeconomic impact of moderate-to-severe versus mild influenza in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Novel viral vectored vaccines for the prevention of influenza.Molecular medicine (Cambridge, Mass.) · 2012Review
- Signs and symptoms predicting influenza in children: a matched case-control analysis of prospectively collected clinical data.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Admission diagnoses of children 0-16 years of age hospitalized with influenza.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Prevalence of antibodies against seasonal influenza A and B viruses in children in Netherlands.Clinical and vaccine immunology : CVI · 2011Article
- Influenza vaccination in the face of immune exhaustion: is herd immunity effective for protecting the elderly?Influenza research and treatment · 2011Article
- Controlling influenza by cytotoxic T-cells: calling for help from destroyers.Journal of biomedicine & biotechnology · 2010Article
- Seroprevalence of influenza A and B in German infants and adolescents.Medical microbiology and immunology · 2009Article
- Article
- The impact of influenza on working days lost: a review of the literature.PharmacoEconomics · 2008Review
- Should healthy children be vaccinated against influenza? Comments about this query.European journal of pediatrics · 2007Article
- We will have to vaccinate healthy children against influenza when we know that it is helpful.European journal of pediatrics · 2006Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Influenza is often regarded as an illness of the elderly portion of the population because most of the excess mortality associated with influenza epidemics occurs in that age group. However, evidence derived from a large number of clinical studies carried out in different countries and various settings has clearly demonstrated that the burden of influenza is also substantial in children. The attack rates of influenza during annual epidemics are consistently highest in children, and young children are hospitalized for influenza-related illnesses at rates comparable to those for adults with high-risk conditions. Especially among children younger than 3 years of age, influenza frequently predisposes the patient to bacterial complications such as acute otitis media. Children also serve as the main transmitters of influenza in the community. A safe and effective vaccine against influenza has been available for decades, but the vaccine is rarely used even for children with high-risk conditions. Despite several existing problems related to influenza vaccination of children, the current evidence indicates that the advantages of vaccinating young children would clearly outweigh the disadvantages. Considering the total burden of influenza in children, children younger than 3 years of age should be regarded as a high-risk group for influenza, analogously with the age-based definition of high risk among persons 65 years of age or older. Annual influenza vaccination should be recommended to all children from 6 months to 3 years of age.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.